An i‐motif is a non‐canonical DNA structure implicated in gene regulation and linked to
cancers. The C‐rich strand of the HRAS oncogene, 5′‐CG CCC GTG CCC TGCG CCC …

G-quadruplexes (G4s) have long been implicated in the regulation of chromatin packaging
and gene expression. These processes require or are accelerated by the separation of …

The development of methods that enabled genome-wide mapping of DNA G-quadruplex
structures in chromatin has played a critical role in providing evidence to support the …

Guanine quadruplexes (G4s) play essential protective and regulatory roles within cells,
influencing gene expression. In several gene-promoter regions, multiple G4-forming …

Guanine-rich DNA can fold into highly stable four-stranded DNA structures called G-
quadruplexes (G4). Originally identified in sequences from telomeres and oncogene …

Bimolecular or tetramolecular G-quadruplexes (GQs) are predominantly self-assembled by
the same sequence-identical G-rich oligonucleotides and usually remain inert to the strand …

Despite numerous reports on the interactions of G-quadruplexes (G4s) with helicases,
systematic analysis addressing the selectivity and specificity of each helicase towards a …

In nucleotide expansion disorders, RNA foci are reportedly associated with
neurodegenerative disease pathogeneses. Characteristically, these RNAs exhibit long poly …

Simple Summary Genomic instability is an important feature of cancer, including multiple
myeloma, which is the second most common hematological malignancy. There are several …

A PfAgo-G4 sensing platform exploiting G4 as a signal reporter was proposed, validated,
and optimized. By introducing two mismatches at the Link strand, a universal nucleotide …