Now 30 years old, the chronic mild stress (CMS) model of depression has been used in>
1300 published studies, with a year-on-year increase rising to> 200 papers in 2015. Data …

In the mammalian central nervous system, reactive oxygen species (ROS) generation is
counterbalanced by antioxidant defenses. When large amounts of ROS accumulate …

Many studies support a crucial role for oxidative & nitrosative stress (O&NS) in the
pathophysiology of unipolar and bipolar depression. These disorders are characterized inter …

Chronic stress triggers activation of the sympathetic nervous system and drives malignancy.
Using an immunodeficient murine system, we showed that chronic stress–induced …

Stress-related disorders, such as depression and anxiety, present marked deficits in
behavioral and cognitive functions related to reward. These are highly prevalent disabling …

Objective To perform a systematic review and meta-analysis that quantitatively tests and
summarizes the hypothesis that depression results in elevated oxidative stress and lower …

Background: Major causative factor for major depression is inflammation, autoimmune tissue
damage and prolonged psychological stress, which leads to oxidative stress. The aim of this …

Synaptic plasticity confers environmental adaptability through modification of the
connectivity between neurons and neuronal circuits. This is achieved through changes to …

Psychological stresses are associated with cardiovascular diseases to the extent that
cardiovascular diseases are among the most important group of psychosomatic diseases …

This study was aimed to evaluate the effects of near-infrared (NIR) photobiomodulation
(PBM) combined with coenzyme Q 10 (CoQ 10) on depressive-like behavior, cerebral …