Trillions of microbes survive and thrive inside the human body. These tiny creatures are
crucial to the development and maturation of our immune system and to maintain gut …

MicroRNAs are small non-coding RNAs regulating gene expression at the post-
transcriptional level. The regulation of microRNA expression in the gut intestine is gradually …

MicroRNA-21 (miR-21) is an oncomiR and significantly upregulated in a wide range of
cancers. It is strongly involved in apoptosis and oncogenesis, since most of its reported …

The therapeutic effect of myeloid-derived suppressor cells (MDSCs) in mice with collagen-
induced arthritis (CIA) remains controversial. We analyzed the role of exosomes derived …

MicroRNAs, as non-coding transcripts, modulate gene expression through RNA silencing
under normal physiological conditions. Their aberrant expression has strongly associated …

Differentiation of CD4+ T cells into Th17 cells is an important factor in the onset and
progression of multiple sclerosis (MS) and Th17/Treg imbalance. Little is known about the …

Background The aim of the study was to investigate the effect of platelet-rich plasma (PRP)
on subchondral bone marrow edema (BME) and the level of biomarkers in synovial fluid of …

Inflammatory bowel diseases (IBD), mainly including Crohn's disease and ulcerative colitis,
are characterized by chronic inflammation of the gastrointestinal tract. Despite improvements …

MicroRNAs fine-tune the regulation of Th1/Th17 lymphocyte subsets in multiple sclerosis.
We investigated the expression of miRNAs (previously associated with mycobacterial and …

Background Currently, no suitable clinical marker for detection of septic immunosuppression
is available. We aimed at identifying microRNAs that could serve as biomarkers of T-cell …