Medicinal attributes of 1, 2, 3-triazoles: Current developments
Triazoles are important five-membered heterocyclic scaffold due to their extensive biological
activities. This framework can be readily obtained in good to excellent yields on the …
activities. This framework can be readily obtained in good to excellent yields on the …
New click-chemistry methods for 1, 2, 3-triazoles synthesis: Recent advances and applications
J Totobenazara, AJ Burke - Tetrahedron letters, 2015 - Elsevier
Triazoles find applications in several major technological areas, and especially in drug
discovery. The click-chemistry approaches based on Huisgen's cycloaddition reaction are …
discovery. The click-chemistry approaches based on Huisgen's cycloaddition reaction are …
Organocatalytic routes toward substituted 1, 2, 3-triazoles
The present feature article describes the different organocatalytic routes for the synthesis of
substituted 1, 2, 3-triazoles. This methodology has recently gained much attention due to its …
substituted 1, 2, 3-triazoles. This methodology has recently gained much attention due to its …
Emerging approaches for the synthesis of triazoles: beyond metal-catalyzed and strain-promoted azide–alkyne cycloaddition
Metal-free 1, 3-dipolar cycloaddition reactions have proven to be a powerful tool for the
assembly of key heterocycles, in particular diversely functionalized 1, 2, 3-triazoles. A …
assembly of key heterocycles, in particular diversely functionalized 1, 2, 3-triazoles. A …
Enamine/enolate-mediated organocatalytic azide-carbonyl [3+ 2] cycloaddition reactions for the synthesis of densely functionalized 1, 2, 3-triazoles.
SSV Ramasastry - Angewandte Chemie International …, 2014 - search.ebscohost.com
Organocatalytic click! Recent advances in the metal‐free enamine/enolate‐mediated azide–
carbonyl [3+ 2] cycloaddition reaction are discussed. These approaches require neither a …
carbonyl [3+ 2] cycloaddition reaction are discussed. These approaches require neither a …
A metal-and azide-free multicomponent assembly toward regioselective construction of 1, 5-disubstituted 1, 2, 3-triazoles
JP Wan, S Cao, Y Liu - The Journal of Organic Chemistry, 2015 - ACS Publications
The construction of 1, 5-disubstituted 1, 2, 3-triazoles has been effected through the cascade
dual C–N bond formation, N–N bond formation and an acyl migration-based C–C bond …
dual C–N bond formation, N–N bond formation and an acyl migration-based C–C bond …
An Enolate‐Mediated Organocatalytic Azide–Ketone [3+ 2]‐Cycloaddition Reaction: Regioselective High‐Yielding Synthesis of Fully Decorated 1, 2, 3‐Triazoles
AB Shashank, S Karthik… - … A European Journal, 2014 - Wiley Online Library
An enolate‐mediated organocatalytic azide–ketone [3+ 2]‐cycloaddition (OrgAKC) reaction
of a variety of enolizable arylacetones and deoxybenzoins with aryl azides was developed …
of a variety of enolizable arylacetones and deoxybenzoins with aryl azides was developed …
Synthesis of substituted 1, 2, 3-triazoles via metal-free click cycloaddition reactions and alternative cyclization methods
HB Jalani, AÇ Karagöz, SB Tsogoeva - Synthesis, 2017 - thieme-connect.com
Click chemistry is one of the most efficient and widely used methodologies for selective C–N
bond forming reactions, encompassing the synthesis of 1, 2, 3-triazoles, and it has been …
bond forming reactions, encompassing the synthesis of 1, 2, 3-triazoles, and it has been …
Synthesis of pharmacological relevant 1, 2, 3-triazole and its analogues-A review
R Varala, HB Bollikolla… - Current Organic …, 2021 - ingentaconnect.com
In this review, authors focus mostly on the various synthetic strategies developed so far for 1,
2, 3-triazole scaffold and its derivatives via different approaches such as metal-free, metal …
2, 3-triazole scaffold and its derivatives via different approaches such as metal-free, metal …
Tris (trimethylsilyl) silane and visible-light irradiation: a new metal-and additive-free photochemical process for the synthesis of indoles and oxindoles
GP da Silva, A Ali, RC da Silva, H Jiang… - Chemical …, 2015 - pubs.rsc.org
A combined tris (trimethylsilyl) silane and visible-light-promoted intramolecular reductive
cyclization protocol for the synthesis of indoles and oxindoles has been developed. This …
cyclization protocol for the synthesis of indoles and oxindoles has been developed. This …