Coiled-coil domain-containing (CCDC) proteins: functional roles in general and male reproductive physiology

PP Priyanka, S Yenugu - Reproductive Sciences, 2021 - Springer
The coiled-coil domain-containing (CCDC) proteins have been implicated in a variety of
physiological and pathological processes. Their functional roles vary from their interaction …

Sperm functional genome associated with bull fertility

M Özbek, M Hitit, A Kaya, FD Jousan… - Frontiers in veterinary …, 2021 - frontiersin.org
Bull fertility is an important economic trait in sustainable cattle production, as infertile or
subfertile bulls give rise to large economic losses. Current methods to assess bull fertility are …

[HTML][HTML] Splice2Deep: An ensemble of deep convolutional neural networks for improved splice site prediction in genomic DNA

S Albaradei, A Magana-Mora, M Thafar, M Uludag… - Gene, 2020 - Elsevier
Background The accurate identification of the exon/intron boundaries is critical for the
correct annotation of genes with multiple exons. Donor and acceptor splice sites (SS) …

CCDC189 affects sperm flagellum formation by interacting with CABCOCO1

M Wang, J Kang, Z Shen, Y Hu, M Chen… - National Science …, 2023 - academic.oup.com
Multiple morphological abnormalities of the sperm flagella (MMAF) are one of the major
causes of male infertility and are characterized by multiple defects. In this study, we found …

Activation of cryptic splicing in bovine WDR19 is associated with reduced semen quality and male fertility

M Hiltpold, G Niu, NK Kadri, D Crysnanto, ZH Fang… - PLoS …, 2020 - journals.plos.org
Cattle are ideally suited to investigate the genetics of male reproduction, because semen
quality and fertility are recorded for all ejaculates of artificial insemination bulls. We analysed …

Autosomal recessive loci contribute significantly to quantitative variation of male fertility in a dairy cattle population

M Hiltpold, NK Kadri, F Janett, U Witschi… - BMC genomics, 2021 - Springer
Background Cattle are ideally suited to investigate the genetics of male fertility. Semen from
individual bulls is used for thousands of artificial inseminations for which the fertilization …

[HTML][HTML] Genome-wide detection of non-additive quantitative trait loci for semen production traits in beef and dairy bulls

R Nagai, M Kinukawa, T Watanabe, A Ogino, K Kurogi… - Animal, 2022 - Elsevier
Semen production traits are important aspects of bull fertility, because semen quantity leads
to direct profits for artificial insemination centres, and semen quality is associated with the …

[HTML][HTML] Genetic mutations affecting bull fertility

H Pausch, XM Mapel - animal, 2023 - Elsevier
Cattle are a well-suited “model organism” to study the genetic underpinnings of variation in
male reproductive performance. The adoption of artificial insemination and genomic …

Adenylate kinase 9 is essential for sperm function and male fertility in mammals

E O'Callaghan, P Navarrete-Lopez… - Proceedings of the …, 2023 - National Acad Sciences
Despite passing routine laboratory tests for semen quality, bulls used in artificial
insemination exhibit significant variation in fertility. Routine analysis of fertility data identified …

Central apparatus, the molecular kickstarter of ciliary and flagellar nanomachines

Z Samsel, J Sekretarska, A Osinka, D Wloga… - International Journal of …, 2021 - mdpi.com
Motile cilia and homologous organelles, the flagella, are an early evolutionarily invention,
enabling primitive eukaryotic cells to survive and reproduce. In animals, cilia have …