Microfluidics-based strategies for molecular diagnostics of infectious diseases

X Wang, XZ Hong, YW Li, Y Li, J Wang, P Chen… - Military Medical …, 2022 - Springer
Traditional diagnostic strategies for infectious disease detection require benchtop
instruments that are inappropriate for point-of-care testing (POCT). Emerging microfluidics, a …

Point of care sensors for infectious pathogens

M Sharafeldin, JJ Davis - Analytical Chemistry, 2020 - ACS Publications
In the wake of the COVID-19 pandemic, the World Health Organization (WHO) has called for
an urgent global collaboration to develop fast, simple, and accurate tests capable of curbing …

A microfluidic chemiluminescence biosensor based on multiple signal amplification for rapid and sensitive detection of E. coli O157: H7

D Sun, T Fan, F Liu, F Wang, D Gao, JM Lin - Biosensors and Bioelectronics, 2022 - Elsevier
Abstract E. coli O157: H7 has become a crucial foodborne pathogen with certain morbidity
and mortality. However, the available methods still face the significant challenges including …

Recent advances on magnetic nanobead based biosensors: From separation to detection

L Wang, J Lin - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Magnetic nanobeads have been widely used for magnetic separation, target labeling and
signal amplification in the development of various biosensors. This review summarized (1) …

A review on microfluidics-based impedance biosensors

YS Chen, CH Huang, PC Pai, J Seo, KF Lei - Biosensors, 2023 - mdpi.com
Electrical impedance biosensors are powerful and continuously being developed for various
biological sensing applications. In this line, the sensitivity of impedance biosensors …

The point-of-care-testing of nucleic acids by chip, cartridge and paper sensors

Y Xu, T Wang, Z Chen, L Jin, Z Wu, J Yan, X Zhao… - Chinese Chemical …, 2021 - Elsevier
Point-of-care nucleic acid testing (POCNAT) has played an important role in the outbreak of
infectious diseases (eg, COVID-19) over recent years. POCNAT aims to realize the rapid …

Electrochemical nucleic acid‐based sensors for detection of Escherichia coli and Shiga toxin‐producing E. coli—Review of the recent developments

LA Wasiewska, VB Juska, I Seymour… - … Reviews in Food …, 2023 - Wiley Online Library
Escherichia coli are a group of bacteria that are a natural part of the intestinal flora of warm‐
blooded animals, including humans. Most E. coli are nonpathogenic and essential for the …

Microfluidic devices for multiplexed detection of foodborne pathogens

X Han, Y Liu, J Yin, M Yue, Y Mu - Food Research International, 2021 - Elsevier
The global burden of foodborne diseases is substantial and foodborne pathogens are the
major cause for human illnesses. In order to prevent the spread of foodborne pathogens …

Lab in a tube: isolation, extraction, and isothermal amplification detection of exosomal long noncoding RNA of gastric cancer

Q Lin, Z Huang, X Ye, B Yang, X Fang, B Liu, H Chen… - Talanta, 2021 - Elsevier
Tumor-derived exosomes that inherit molecular information on parental cells hold great
promise for cancer diagnostics. Currently, two main technical challenges, time-consuming …

Conductivity-Regulated Bipolar Electrochemiluminescence Sensing Platform for Indicator-Free Homogeneous Bioassay

J Ni, B Yang, L Liu, X Dai, W Yang, Q Wang… - Analytical …, 2024 - ACS Publications
Electrochemiluminescence (ECL) sensors have been widely developed because of their
high sensitivity and low background. However, most of them suffered from tedious probe …