Extracellular vesicles as next generation immunotherapeutics

DW Greening, R Xu, A Ale, CE Hagemeyer… - Seminars in Cancer …, 2023 - Elsevier
Extracellular vesicles (EVs) function as a mode of intercellular communication and
molecular transfer to elicit diverse biological/functional response. Accumulating evidence …

[HTML][HTML] Targeting lipid metabolism of macrophages: A new strategy for tumor therapy

N Shao, H Qiu, J Liu, D Xiao, J Zhao, C Chen… - Journal of Advanced …, 2024 - Elsevier
Background Lipid metabolism has been implicated in a variety of normal cellular processes
and strongly related to the development of multiple diseases, including tumor. Tumor …

[HTML][HTML] Exosomes: diagnostic and therapeutic implications in cancer

H Jo, K Shim, D Jeoung - Pharmaceutics, 2023 - mdpi.com
Exosomes are a subset of extracellular vesicles produced by all cells, and they are present
in various body fluids. Exosomes play crucial roles in tumor initiation/progression, immune …

Functionalization of seawater reverse osmosis membrane with quorum sensing inhibitor to regulate microbial community and mitigate membrane biofouling

C Chen, Y Yang, CH Lee, S Takizawa, Z Zhang, HY Ng… - Water Research, 2024 - Elsevier
Membrane biofouling is a challenge to be solved for the stable operation of the seawater
reverse osmosis (SWRO) membrane. This study explored the regulation mechanism of …

Co-delivery of oxaliplatin prodrug liposomes with Bacillus Calmette-Guerin for chemo-immunotherapy of orthotopic bladder cancer

C Ma, X Zhong, R Liu, X Yang, Z Xie, Y Zhang… - Journal of Controlled …, 2024 - Elsevier
To reduce recurrence rate after transurethral resection of bladder tumor, long-term
intravesical instillations of Bacillus Calmette-Guérin (BCG) and/or chemotherapeutic drugs is …

Black phosphorus nanosheets grafted with gold nanorods and carbon nanodots for synergistic antitumor therapy

J Zhu, N Ouyang, R Zhao, Z Guo, J Yang… - … Applied Materials & …, 2023 - ACS Publications
Synergetic photothermal/photodynamic/chemotherapy receives significant attention for
precise in vivo cancer treatment. Despite plenty of encouraging photosensitizers explored …

Dual gatekeepers-modified mesoporous organic silica nanoparticles for synergistic photothermal-chemotherapy of breast cancer

W Wang, F Zhong, D Wang, Y Zhao, D Peng… - Journal of Colloid and …, 2023 - Elsevier
Hypothesis Construction of dual gatekeepers-functionalized mesoporous organic silica
nanoparticles (MONs) with both physical and chemical mechanisms for modulated drug …

[HTML][HTML] CD36 as a double-edged sword in cancer

M Jiang, R Karsenberg, F Bianchi, G van den Bogaart - Immunology Letters, 2023 - Elsevier
The membrane protein CD36 is a lipid transporter, scavenger receptor, and receptor for the
antiangiogenic protein thrombospondin 1 (TSP1). CD36 is expressed by cancer cells and by …

[HTML][HTML] Unlocking the therapeutic applicability of LNP-mRNA: Chemistry, formulation, and clinical strategies

X Huang, Y Ma, G Ma, Y Xia - Research, 2024 - spj.science.org
Messenger RNA (mRNA) has emerged as an innovative therapeutic modality, offering
promising avenues for the prevention and treatment of a variety of diseases. The …

The role of phospholipids in drug delivery formulations–Recent advances presented at the Researcher's Day 2023 Conference of the Phospholipid Research Center …

R Wibel, P van Hoogevest, S Drescher - European Journal of …, 2024 - Elsevier
Abstract This Focus on Meetings contribution summarizes recent advances in the research
on phospholipids and their applications for drug delivery and analytical purposes that have …