Massively parallel sequencing identifies pathogenic variants in the genes affected in Alport
syndrome (COL4A3–COL4A5) in as many as 30% of individuals with focal and segmental …

IgA nephropathy (IgAN) is observed in subjects of any age, however perspective and
management of this disease are different between adult and pediatrician Nephrologists …

Methods In this prospective cohort study, we undertook genetic testing in adults with
suspected GKD according to prespecified criteria. Over 7 years, patients were referred from …

Immunoglobulin A (IgA) nephropathy (IgAN), the most common form of glomerulonephritis, is
one of the leading causes of end-stage kidney disease (ESKD). It is widely believed that …

Abstract Background IgA nephropathy (IgAN) is the most common primary
glomerulonephritis worldwide. Although most IgAN cases are sporadic, few show a familial …

For many years renal biopsy has been the gold standard for diagnosis in many forms of
kidney disease. It provides rapid, accurate and clinically useful information in most …

Alport syndrome (AS) is a clinically and genetically heterogeneous disorder with a wide
phenotypic spectrum, onset, and progression. X-linked AS (XLAS) and autosomal recessive …

Abstract Background Alport Syndrome and IgA Nephropathy (IgAN) are both disorders that
can cause hematuria. Alport syndrome is most commonly an X-linked disease, caused by …

Introduction: IgA nephropathy is the most common primary glomerulonephritis among adults
in clinic. Thin basement membrane nephropathy is often underestimated or even omitted if it …

Immunoglobulin A (IgA) nephropathy (IgAN) is the most common type of primary
glomerulonephritis worldwide. In addition to hematuria, proteinuria is observed in a …