Resilience of the oral microbiota in health: mechanisms that prevent dysbiosis

BT Rosier, PD Marsh, A Mira - Journal of dental research, 2018 - journals.sagepub.com
Dental diseases are now viewed as a consequence of a deleterious shift in the balance of
the normally stable resident oral microbiome. It is known that frequent carbohydrate …

Aerobic denitrification: a review of important advances of the last 30 years

B Ji, K Yang, L Zhu, Y Jiang, H Wang, J Zhou… - Biotechnology and …, 2015 - Springer
Understanding aerobic denitrification has become an important focus of environmental
microbiology. Aerobic denitrification can be performed by various genera of microorganisms …

Strains, functions and dynamics in the expanded Human Microbiome Project

J Lloyd-Price, A Mahurkar, G Rahnavard, J Crabtree… - Nature, 2017 - nature.com
The characterization of baseline microbial and functional diversity in the human microbiome
has enabled studies of microbiome-related disease, diversity, biogeography, and molecular …

The importance of nitrate reduction for oral health

BT Rosier, N Takahashi, E Zaura… - Journal of dental …, 2022 - journals.sagepub.com
Salivary glands concentrate plasma nitrate into saliva, leading to high nitrate concentrations
that can reach the millimolar range after a nitrate-rich vegetable meal. Whereas human cells …

Nitrate as a potential prebiotic for the oral microbiome

BT Rosier, E Buetas, EM Moya-Gonzalvez, A Artacho… - Scientific reports, 2020 - nature.com
The salivary glands actively concentrate plasma nitrate, leading to high salivary nitrate
concentrations (5–8 mM) after a nitrate-rich vegetable meal. Nitrate is an ecological factor …

Nitrate reduction to nitrite, nitric oxide and ammonia by gut bacteria under physiological conditions

M Tiso, AN Schechter - PloS one, 2015 - journals.plos.org
The biological nitrogen cycle involves step-wise reduction of nitrogen oxides to ammonium
salts and oxidation of ammonia back to nitrites and nitrates by plants and bacteria. Neither …

Nitric oxide and nitrous oxide turnover in natural and engineered microbial communities: biological pathways, chemical reactions, and novel technologies

F Schreiber, P Wunderlin, KM Udert… - Frontiers in …, 2012 - frontiersin.org
Nitrous oxide (N2O) is an environmentally important atmospheric trace gas because it is an
effective greenhouse gas and it leads to ozone depletion through photo-chemical nitric …

How biology handles nitrite

LB Maia, JJG Moura - Chemical Reviews, 2014 - ACS Publications
Nitrite is one of the players in the broad nitrogen biogeochemical cycle. This nitrogen oxo-
anion is involved in key pathways crucial to life on Earth and to the planetary “recycling” of …

Enterosalivary nitrate metabolism and the microbiome: intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health

CD Koch, MT Gladwin, BA Freeman… - Free Radical Biology …, 2017 - Elsevier
Recent insights into the bioactivation and signaling actions of inorganic, dietary nitrate and
nitrite now suggest a critical role for the microbiome in the development of cardiac and …

The oral microbiome and nitric oxide homoeostasis

MP Hezel, E Weitzberg - Oral diseases, 2015 - Wiley Online Library
The tiny radical nitric oxide (NO) participates in a vast number of physiological functions
including vasodilation, nerve transmission, host defence and cellular energetics. Classically …