Recent advances in high-throughput technologies have enabled the profiling of multiple
layers of a biological system, including DNA sequence data (genomics), RNA expression …

Metabolomics comprises the methods and techniques that are used to measure the small
molecule composition of biofluids and tissues, and is actually one of the most rapidly …

Metabolic profiling of cancer cells has recently been established as a promising tool for the
development of therapies and identification of cancer biomarkers. Here we characterized the …

Background Recently, rapid advances have been made in metabolomics-based, easy-to-
use early cancer detection methods using blood samples. Among metabolites, profiling of …

Individual variations in drug efficacy, side effects and adverse drug reactions are still
challenging that cannot be ignored in drug research and development. The aim of …

Introduction Remodeling of cellular metabolism appears to be a consequence and possibly
a cause of oncogenic transformation in human cancers. Specific aspects of altered tumor …

Breast cancer (BC) is characterized by an extensive genotypic and phenotypic
heterogeneity. In-depth investigations into the molecular bases of BC phenotypes …

Background The aims of this study were to characterize the metabolite profiles of triple
negative breast cancer (TNBC) and to investigate the metabolite profiles associated with …

Metabolomic approaches have been used to identify new diagnostic biomarkers for various
types of cancers, including breast cancer. In this study, we aimed to identify potential …

Background More accurate diagnostic methods are pressingly needed to diagnose breast
cancer, the most common malignant cancer in women worldwide. Blood-based …