Cancer cells alter metabolic processes to sustain their characteristic uncontrolled growth
and proliferation. These metabolic alterations include (1) a shift from oxidative …

Branched-chain amino acids (BCAAs) are critical for skeletal muscle and whole-body
anabolism and energy homeostasis. They also serve as signaling molecules, for example …

Increased intracellular toxicity due to an imbalance in copper homeostasis caused by
copper ion accumulation could regulate the rate of cancer cell growth and proliferation. The …

The immunotherapeutic effect elicited by photodynamic therapy (PDT) is attenuated by
tumor defense mechanisms associated with glutamine metabolism, including the metabolic …

Tumor microenvironment (TME), which is characterized by hypoxia, widely exists in solid
tumors. As a current research hotspot in the TME, hypoxia is expected to become a key …

Abstract N 6-methyladenosine (m6A) is a eukaryotic post-transcriptional modification
involved in cell growth and developmental processes, including RNA transcription …

Colorectal cancer (CRC) is the third most common cancer in the world. Although there are
standard treatment options for CRC, most patients respond poorly to these treatments …

In spite of substantial progress made toward understanding cancer pathogenesis, this
disease remains one of the leading causes of mortality. Thus, there is an urgent need to …

Targeted therapies against cancer have improved both survival and quality of life of patients.
However, metabolic rewiring evokes cellular mechanisms that reduce therapeutic …

Significant progress in understanding cancer pathogenesis, it remains one of the leading
causes of death after cardiovascular diseases. Similarly viral infections have emerged from …