Natural coumarins: exploring the pharmacological complexity and underlying molecular mechanisms

J Sharifi-Rad, N Cruz-Martins… - Oxidative Medicine …, 2021 - Wiley Online Library
Coumarins belong to the benzopyrone family commonly found in many medicinal plants.
Natural coumarins demonstrated a wide spectrum of pharmacological activities, including …

Diosgenin: an updated pharmacological review and therapeutic perspectives

P Semwal, S Painuli, T Abu-Izneid… - Oxidative medicine …, 2022 - Wiley Online Library
Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain
a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high …

Urtica dioica‐Derived Phytochemicals for Pharmacological and Therapeutic Applications

Y Taheri, C Quispe, J Herrera-Bravo… - Evidence‐based …, 2022 - Wiley Online Library
Urtica dioica belongs to the Urticaceae family and is found in many countries around the
world. This plant contains a broad range of phytochemicals, such as phenolic compounds …

[HTML][HTML] The polypharmacological effects of cannabidiol

J Castillo-Arellano, A Canseco-Alba, SJ Cutler, F León - Molecules, 2023 - mdpi.com
Cannabidiol (CBD) is a major phytocannabinoid present in Cannabis sativa (Linneo, 1753).
This naturally occurring secondary metabolite does not induce intoxication or exhibit the …

[HTML][HTML] Phenolic compounds as Nrf2 inhibitors: potential applications in cancer therapy

J Sharifi-Rad, V Seidel, M Izabela… - Cell Communication and …, 2023 - Springer
Cancer is a leading cause of death worldwide and involves an oxidative stress mechanism.
The transcription factor Nrf2 has a crucial role in cytoprotective response against oxidative …

[HTML][HTML] Myricetin: targeting signaling networks in cancer and its implication in chemotherapy

Z Javed, K Khan, J Herrera-Bravo, S Naeem… - Cancer Cell …, 2022 - Springer
The gaps between the complex nature of cancer and therapeutics have been narrowed
down due to extensive research in molecular oncology. Despite gathering massive insight …

Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles

J Sharifi-Rad, J Herrera-Bravo… - Oxidative Medicine …, 2022 - Wiley Online Library
Artemisia plants are traditional and ethnopharmacologically used to treat several diseases
and in addition in food, spices, and beverages. The genus is widely distributed in all …

[HTML][HTML] Anticancer properties of bromelain: State-of-the-art and recent trends

R Pezzani, M Jimenez-Garcia, X Capo… - Frontiers in …, 2023 - frontiersin.org
Bromelain is a key enzyme found in pineapple (Ananas comosus (L.) Merr.); a proteolytic
substance with multiple beneficial effects for human health such as anti-inflammatory …

[HTML][HTML] Camellia sinensis: insights on its molecular mechanisms of action towards nutraceutical, anticancer potential and other therapeutic applications

P Chaudhary, D Mitra, PKD Mohapatra… - Arabian Journal of …, 2023 - Elsevier
The Camellia sinensis plant provides a wide diversity of black, green, oolong, yellow, brick
dark, and white tea. Tea is one of the majorly used beverages across the globe, succeeds …

A Literature‐Based Update on Benincasa hispida (Thunb.) Cogn.: Traditional Uses, Nutraceutical, and Phytopharmacological Profiles

MT Islam, C Quispe, DM El-Kersh… - Oxidative medicine …, 2021 - Wiley Online Library
Benincasa hispida (Thunb.) Cogn.(Cucurbitaceae) is an annual climbing plant, native to
Asia with multiple therapeutic uses in traditional medicine. This updated review is aimed at …