Bone Morphogenetic Proteins (BMPs) play an important role during organ development and
during regeneration after tissue damage. BMPs signal via transmembrane serine/threonine …

Bone marrow-derived mesenchymal stem and stromal cells (MSCs) are promising
candidates for cell-based therapies in diverse conditions including tissue engineering …

Aim: To determine whether fluid flow-induced shear stress affects the differentiation of bone
marrow-derived human mesenchymal stem cells (hMSCs) into osteogenic cells. Materials & …

Bone tissue engineering aims to generate clinically applicable bone graft substitutes in an
effort to ease the demands and reduce the potential risks associated with traditional …

Tissue engineering has emerged as a possible alternative to current treatments for bone
injuries and defects. However, the common tissue engineering approach presents some …

Bone mesenchymal stem cells (BMSCs) are crucial for bone tissue regeneration, the
mechanical microenvironment of hard tissues, including bone and teeth, significantly affects …

A potent regulator of bone anabolism is physical loading. However, it is currently unclear
whether physical stimuli such as fluid shear within the marrow cavity is sufficient to directly …

This eight-chapter monograph intends to present basic principles and applications of
biomechanics in bone tissue engineering in order to assist tissue engineers in design and …

Bone marrow-derived multipotent stem and stromal cells (MSCs) are likely candidates for
cell-based therapies for various conditions including skeletal disease. Advancement of …

Mechanical stimuli can improve bone function by promoting the proliferation and
differentiation of bone cells and osteoblasts. As precursors of osteoblasts, human …