Dissecting the role of subtypes of gastrointestinal vagal afferents
Gastrointestinal (GI) vagal afferents convey sensory signals from the GI tract to the brain.
Numerous subtypes of GI vagal afferent have been identified but their individual roles in gut …
Numerous subtypes of GI vagal afferent have been identified but their individual roles in gut …
Proposal open for discussion: defining agreed diagnostic procedures in experimental diabetes research
E Matteucci, O Giampietro - Journal of ethnopharmacology, 2008 - Elsevier
BACKGROUND: Animal experimentation has a long tradition in diabetes research and has
provided invaluable benefits with regard to insulin discovery and treatment assessment …
provided invaluable benefits with regard to insulin discovery and treatment assessment …
Weight loss during chronic, cervical vagus nerve stimulation in depressed patients with obesity: an observation
JV Pardo, SA Sheikh, MA Kuskowski… - International journal of …, 2007 - nature.com
Fourteen patients were treated over 2 years with cervical vagus nerve stimulation (VNS) for
adjunctive therapy of severe, treatment-resistant depression. Here, we report the …
adjunctive therapy of severe, treatment-resistant depression. Here, we report the …
Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat
BP Cummings, EK Digitale… - American Journal …, 2008 - journals.physiology.org
The prevalence of type 2 diabetes (T2DM) is increasing, creating a need for T2DM animal
models for the study of disease pathogenesis, prevention, and treatment. The purpose of this …
models for the study of disease pathogenesis, prevention, and treatment. The purpose of this …
Anorexia‐cachexia syndrome in hepatoma tumour‐bearing rats requires the area postrema but not vagal afferents and is paralleled by increased MIC‐1/GDF15
Background The cancer‐anorexia‐cachexia syndrome (CACS) negatively affects survival
and therapy success in cancer patients. Inflammatory mediators and tumour‐derived factors …
and therapy success in cancer patients. Inflammatory mediators and tumour‐derived factors …
Glucose effectiveness: Lessons from studies on insulin‐independent glucose clearance in mice
B Ahrén, G Pacini - Journal of Diabetes Investigation, 2021 - Wiley Online Library
Besides insulin‐mediated transport of glucose into the cells, an important role is also played
by the non‐insulin‐mediated transport. This latter process is called glucose effectiveness …
by the non‐insulin‐mediated transport. This latter process is called glucose effectiveness …
Cholecystokinin/Cholecystokinin-1 receptor-mediated peripheral activation of the afferent vagus by enteral nutrients attenuates inflammation in rats
T Lubbers, JJ de Haan, MDP Luyer, I Verbaeys… - Annals of …, 2010 - journals.lww.com
Objective: The current study investigates activation of the nutritional anti-inflammatory
pathway by lipid-rich nutrition. Background: Enteral nutrition activates humoral and neural …
pathway by lipid-rich nutrition. Background: Enteral nutrition activates humoral and neural …
Cervical vagal stimulation induced weight loss
JV Pardo, SA Sheikh - US Patent 8,064,994, 2011 - Google Patents
5,215,086 A 6/1993 Terry, Jr. et al. 5,222.494. A 6/1993 Baker, Jr. 5,231,988 A 8, 1993
Wernicke et al. 5,235,980 A 8, 1993 Varrichio et al. 5,263,480 A 11/1993 Wernicke et al …
Wernicke et al. 5,235,980 A 8, 1993 Varrichio et al. 5,263,480 A 11/1993 Wernicke et al …
[图书][B] Handbook of Laboratory Animal Science: Animal Models, Volume II
J Hau, SJ Schapiro, GL Van Hoosier Jr - 2002 - taylorfrancis.com
The conservative nature of animal evolution makes animal models the ideal tool for learning
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …
Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats [S]
Acyl CoA: diacylglycerol acyltransferase-1 (DGAT-1) catalyzes the final step in triacylglycerol
(TAG) synthesis and is highly expressed in the small intestine. Because DGAT-1 knockout …
(TAG) synthesis and is highly expressed in the small intestine. Because DGAT-1 knockout …