Bioinspired shielding strategies for nanoparticle drug delivery applications

NM Gulati, PL Stewart, NF Steinmetz - Molecular pharmaceutics, 2018 - ACS Publications
Nanoparticle delivery systems offer advantages over free drugs, in that they increase
solubility and biocompatibility. Nanoparticles can deliver a high payload of therapeutic …

The intelligent delivery systems for bioactive compounds in foods: Physicochemical and physiological conditions, absorption mechanisms, obstacles and responsive …

J Chai, P Jiang, P Wang, Y Jiang, D Li, W Bao… - Trends in Food Science …, 2018 - Elsevier
Background Bioactive natural compounds have received considerable attention due to their
health benefits, including anti-oxidant, anti-cancer, anti-diabetes and cardiovascular disease …

L-Carnitine-conjugated nanoparticles to promote permeation across blood–brain barrier and to target glioma cells for drug delivery via the novel organic cation …

L Kou, Y Hou, Q Yao, W Guo, G Wang… - Artificial cells …, 2018 - Taylor & Francis
Overcoming blood–brain barrier (BBB) and targeting tumor cells are two key steps for glioma
chemotherapy. By taking advantage of the specific expression of Na+-coupled carnitine …

Development of a novel microemulsion for oral absorption enhancement of all-trans retinoic acid

T Subongkot, T Ngawhirunpat - International Journal of …, 2017 - Taylor & Francis
This study was aimed to develop a novel microemulsion that contained oleth-5 as a
surfactant to enhance the oral absorption of all-trans retinoic acid (ATRA). The prepared …

Synthesis of photoresponsive polymeric propesticide micelles based on PEG for the controlled release of a herbicide

K Ding, L Shi, L Zhang, T Zeng, Y Yin, Y Yi - Polymer Chemistry, 2016 - pubs.rsc.org
A novel amphiphilic polymer–pesticide conjugate was synthesized by conjugation of PEG
with the photolabile o-nitrobenzyl group followed by grafting dichlorophenoxyacetic acid (2 …

Enhanced oral bioavailability, anti-tumor activity and hepatoprotective effect of 6-shogaol loaded in a type of novel micelles of polyethylene glycol and linoleic acid …

H Zhang, Q Wang, C Sun, Y Zhu, Q Yang, Q Wei… - Pharmaceutics, 2019 - mdpi.com
6-shogaol is a promising anti-cancer and anti-inflammatory agent. However, the treatment
effectiveness of 6-shogaol is limited by poor water solubility, poor oral absorption and rapid …

[HTML][HTML] The studies of PLGA nanoparticles loading atorvastatin calcium for oral administration in vitro and in vivo

Z Li, W Tao, D Zhang, C Wu, B Song, S Wang… - asian journal of …, 2017 - Elsevier
A biodegradable poly (lactic-co-glycolic acid) loading atorvastatin calcium (AC)
nanoparticles (AC-PLGA-NPs) were prepared by probe ultrasonication and evaporation …

Synthesis of PLGA–mPEG star-like block copolymer to form micelle loaded magnetite as a nanocarrier for hydrophobic anticancer drug

M Ashjari, F Panahandeh, Z Niazi… - Journal of Drug Delivery …, 2020 - Elsevier
The current work focuses on synthesis of a novel nanocarrier containing quercetin drug and
equipped with superparamagnetic property for biological applications. The biodegradable …

Evaluation of the cytotoxicity, genotoxicity and mucus permeation capacity of several surface modified poly (anhydride) nanoparticles designed for oral drug delivery

T Iglesias, AL de Cerain, JM Irache… - International journal of …, 2017 - Elsevier
The main concerns with drugs designed for oral administration are their inactivation or
degradation in the harsh conditions of the gastrointestinal tract, their poor solubility through …

Improved oral bioavailability, cellular uptake, and cytotoxic activity of zingerone via nano-micelles drug delivery system

Z Ge, Q Wang, Q Zhu, M Yusif, J Yu… - Journal of …, 2021 - Taylor & Francis
Herein, a nano-micelle drug delivery system was developed to orally improved zingerone's
bioavailability and its antitumor effect. Indeed, zingerone-loaded d-α-tocopheryl …