Metabolic engineering strategies for microbial synthesis of oleochemicals
Microbial synthesis of oleochemicals has advanced significantly in the last decade.
Microbes have been engineered to convert renewable substrates to a wide range of …
Microbes have been engineered to convert renewable substrates to a wide range of …
Natural products as biofuels and bio-based chemicals: fatty acids and isoprenoids
Covering: 2005 to 2015 Although natural products are best known for their use in medicine
and agriculture, a number of fatty acid-derived and isoprenoid natural products are being …
and agriculture, a number of fatty acid-derived and isoprenoid natural products are being …
Rescuing yeast from cell death enables overproduction of fatty acids from sole methanol
J Gao, Y Li, W Yu, YJ Zhou - Nature Metabolism, 2022 - nature.com
Methanol is an ideal feedstock for biomanufacturing that can be beneficial for global carbon
neutrality; however, the toxicity of methanol limits the efficiency of methanol metabolism …
neutrality; however, the toxicity of methanol limits the efficiency of methanol metabolism …
[HTML][HTML] Production of fatty acid-derived oleochemicals and biofuels by synthetic yeast cell factories
Sustainable production of oleochemicals requires establishment of cell factory platform
strains. The yeast Saccharomyces cerevisiae is an attractive cell factory as new strains can …
strains. The yeast Saccharomyces cerevisiae is an attractive cell factory as new strains can …
Viscous control of cellular respiration by membrane lipid composition
Lipid composition determines the physical properties of biological membranes and can vary
substantially between and within organisms. We describe a specific role for the viscosity of …
substantially between and within organisms. We describe a specific role for the viscosity of …
Comprehensive in Vitro Analysis of Acyltransferase Domain Exchanges in Modular Polyketide Synthases and Its Application for Short-Chain Ketone Production
S Yuzawa, K Deng, G Wang, EEK Baidoo… - ACS synthetic …, 2017 - ACS Publications
Type I modular polyketide synthases (PKSs) are polymerases that utilize acyl-CoAs as
substrates. Each polyketide elongation reaction is catalyzed by a set of protein domains …
substrates. Each polyketide elongation reaction is catalyzed by a set of protein domains …
Engineering high-level production of fatty alcohols by Saccharomyces cerevisiae from lignocellulosic feedstocks
Fatty alcohols in the C12-C18 range are used in personal care products, lubricants, and
potentially biofuels. These compounds can be produced from the fatty acid pathway by a …
potentially biofuels. These compounds can be produced from the fatty acid pathway by a …
Metabolic engineering of microalgal based biofuel production: prospects and challenges
The current scenario in renewable energy is focused on development of alternate and
sustainable energy sources, amongst which microalgae stands as one of the promising …
sustainable energy sources, amongst which microalgae stands as one of the promising …
Metabolic engineering of Saccharomyces cerevisiae for the overproduction of short branched-chain fatty acids
AQ Yu, NKP Juwono, JL Foo, SSJ Leong… - Metabolic …, 2016 - Elsevier
Short branched-chain fatty acids (SBCFAs, C4-6) are versatile platform intermediates for the
production of value-added products in the chemical industry. Currently, SBCFAs are mainly …
production of value-added products in the chemical industry. Currently, SBCFAs are mainly …