Importance Pulmonary arterial hypertension (PAH) is a subtype of pulmonary hypertension
(PH), characterized by pulmonary arterial remodeling. The prevalence of PAH is …

Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and may be associated with a variety of cardiovascular and respiratory …

Background Risk stratification plays an essential role in the management of patients with
pulmonary arterial hypertension (PAH). The current European guidelines propose a three …

Guidelines summarize and evaluate available evidence, with the aim of assisting health
professionals in proposing the best management strategies for an individual patient with a …

Background Since 2015, the European pulmonary hypertension guidelines recommend the
use of combination therapy in most patients with pulmonary arterial hypertension (PAH) …

Background Current mortality data for pulmonary arterial hypertension (PAH) in the United
States are based on registries that enrolled patients prior to 2010. We sought to determine …

The pulmonary circulation is a low-resistance, low-pressure, and high-compliance system
that allows the lungs to receive the entire cardiac output. Pulmonary arterial pressure is a …

Despite numerous therapeutic advances in pulmonary arterial hypertension, patients
continue to suffer high morbidity and mortality, particularly considering a median age of 50 …

Pulmonary hypertension (PH) is a serious disease characterized by various degrees of
pulmonary vasoconstriction and progressive fibroproliferative remodeling and inflammation …

Background The evolution in pulmonary arterial hypertension (PAH) management has been
summarised in three iterations of the European Society of Cardiology/European Respiratory …