Impact of Sickle Cell Disease on Affected Individuals in Nigeria: A Critical Review

OP Adigwe, G Onavbavba, SO Onoja - International Journal of …, 2023 - Taylor & Francis
Sickle cell disease is an autosomal recessive disorder of the beta-globin gene, with resultant
deformation of the red blood cells and variable clinical outcomes. Nigeria is recognised as …

Electrocardiographic abnormalities in patients with sickle cell disease: A systematic review and meta‐analysis

E Taherifard, H Movahed, E Taherifard… - Pediatric Blood & …, 2024 - Wiley Online Library
Background Previous studies have documented that electrocardiography (ECG) can reveal
a range of abnormalities, offering valuable insights into the cardiac evaluation of patients …

Associations of prolonged QTc in sickle cell disease

JH Indik, V Nair, R Rafikov, IS Nyotowidjojo, J Bisla… - PloS one, 2016 - journals.plos.org
Sudden death is a leading cause of mortality in sickle cell disease, implicating ventricular
tachyarrhythmias. Prolonged QTc on an electrocardiogram (ECG), commonly seen with …

Evaluation of the Seattle and international criteria in elite Nigerian athletes

TF Ilodibia, JO Odia - Journal of Electrocardiology, 2021 - Elsevier
Abstract Background The Seattle Criteria (SC) and International Criteria (IC) were both
developed for cardiovascular pre-participation screening in young athletes. Neither set of …

Assessment of ventricular repolarization in sickle cell anemia patients: the role of QTc interval, Tp-e interval and Tp-e/QTc ratio and its gender implication

AO Ajibare, OP Olabode, EY Fagbemiro… - Vascular health and …, 2020 - Taylor & Francis
Background Many specific and non-specific electrocardiographic abnormalities including
ventricular arrhythmias have been reported in subjects with sickle cell anemia (SCA). In SCA …

Electrocardiographic study in adult homozygous sickle cell disease patients in Lagos, Nigeria

A Dosunmu, A Akinbami, E Uche… - Journal of tropical …, 2016 - Wiley Online Library
Background. This study sought to identify the pattern of electrocardiographic changes in
steady state adult sickle cell anaemia. Methods. A case‐control, cross‐sectional study was …

Electrocardiographic abnormalities and dyslipidaemic syndrome in children with sickle cell anaemia: cardiovascular topics

SA Adegoke, JAO Okeniyi… - Cardiovascular Journal of …, 2016 - journals.co.za
Background: Lipid and electrocardiographic (ECG) abnormalities have been reported in
adults with sickle cell anaemia (SCA) and may reflect underlying structural and/or functional …

Blood pressure and electrocardiographic profile of children with sickle cell anaemia in steady-state and vaso-occlusive crisis

AT Adeniyi, SA Adegoke, OS Olatunya… - Ghana Medical …, 2023 - ajol.info
Objective: To compare the cardiovascular features of patients with sickle cell anaemia (SCA)
in steady-state with those in vaso-occlusive crisis (VOC) at the Wesley Guild Hospital …

Cardiac autonomic dysfunction in sickle cell anaemia and its correlation with QT parameters

PM Kolo, EO Sanya, TO Olanrewaju, AE Fawibe… - Nigerian Medical …, 2013 - ajol.info
Background: Abnormalities of QT parameters together with cardiac autonomic neuropathy
(CAN) confer significant risks of cardiac morbidity and mortality in patients with diabetes …

Left ventricular geometry and electrocardiographic criteria in assessing left ventricular hypertrophy in sickle cell anemia patients

AA ADEBIYI, AJE Akinyemi, TS AKINGBOLA - Journal of the National …, 2022 - Elsevier
Background Left ventricular hypertrophy (LVH) is recognized as a cardiovascular risk factor
and is a known consequence of sickle cell anemia (SCA). Abnormal left ventricular …