Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine

N Fujiwara, SL Friedman, N Goossens, Y Hoshida - Journal of hepatology, 2018 - Elsevier
Patients who develop chronic fibrotic liver disease, caused by viral or metabolic aetiologies,
are at a high risk of developing hepatocellular carcinoma (HCC). Even after complete HCC …

Update in global trends and aetiology of hepatocellular carcinoma

P Rawla, T Sunkara, P Muralidharan… - Contemporary Oncology …, 2018 - termedia.pl
Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver responsible
for an increasing number of cancer-related deaths, especially in developing economies of …

Hepatitis C-related hepatocellular carcinoma in the era of new generation antivirals

TF Baumert, F Jühling, A Ono, Y Hoshida - BMC medicine, 2017 - Springer
Hepatitis C virus infection is a major cause of hepatocellular carcinoma worldwide.
Interferon has been the major antiviral treatment, yielding viral clearance in approximately …

long‐term safety of nucleoside and nucleotide analogues in HBV‐monoinfected patients

P Lampertico, HLY Chan, HLA Janssen… - Alimentary …, 2016 - Wiley Online Library
Background Nucleos (t) ide analogues (NUC s) for chronic hepatitis B treatment achieve
high rates of viral suppression and are generally well tolerated. Entecavir (ETV) and …

Recent advancements in diagnosis and therapy of liver cirrhosis

R Giulio Romanelli, C Stasi - Current Drug Targets, 2016 - ingentaconnect.com
Cirrhosis is a diffuse pathophysiological state of the liver considered to be the final stage of
various liver injuries, characterized by chronic necroinflammatory and fibrogenetic …

Hepatitis B virus, hepatitis C virus and human immunodeficiency virus infection in undocumented migrants and refugees in southern Italy, January 2012 to June 2013

N Coppola, L Alessio, L Gualdieri, M Pisaturo… - …, 2015 - eurosurveillance.org
Screening of undocumented migrants or refugees for hepatitis B virus (HBV), hepatitis C
virus (HCV) and human immunodeficiency virus (HIV) infections has been offered free of …

[HTML][HTML] Liver fibrosis staging with combination of APRI and FIB-4 scoring systems in chronic hepatitis C as an alternative to transient elastography

N Papadopoulos, S Vasileiadi, M Papavdi… - Annals of …, 2019 - ncbi.nlm.nih.gov
Background: Liver disease severity must be determined before treatment of chronic hepatitis
C (CHC). We evaluated the diagnostic performance of the APRI and FIB-4 scores compared …

Hepatitis B virus long‐term impact of antiviral therapy nucleot (s) ide analogues (NUC s)

G Grossi, M Viganò, A Loglio, P Lampertico - Liver International, 2017 - Wiley Online Library
The goal of antiviral therapy is to improve the quality of life and survival of patients with
chronic hepatitis B (CHB) by halting the progression to cirrhosis, end‐stage liver disease or …

Introduction to hepatitis C virus infection: Overview and history of hepatitis C virus therapies

L Puchades Renau, M Berenguer - Hemodialysis International, 2018 - Wiley Online Library
Chronic hepatitis C virus (HCV) infection is an infection that affects over 71 million people
worldwide that primarily leads to significant morbidity and mortality through its predisposition …

[HTML][HTML] Red blood cell distribution width-to-platelet ratio and other laboratory indices associated with severity of histological hepatic fibrosis in patients with …

X Li, H Xu, P Gao - … Medical Journal of Experimental and Clinical …, 2020 - ncbi.nlm.nih.gov
Background This retrospective study at a single center aimed to evaluate the role of the red
blood cell distribution width (RDW)-to-platelet ratio and other laboratory indices associated …