During their reproductive years women produce significant levels of estrogens,
predominantly in the form of estradiol, that are thought to play an important role in …

Diabetes and cardiometabolic disorders such as hypertension and obesity are major risk
factors for the development of cardiovascular disease, with a wealth of evidence suggesting …

Sweet cherries (Prunus avium L.) are highly appreciated fruits for their taste, color, nutritional
value, and beneficial health effects. In this work, seven new cultivars of sweet cherry were …

Neurodegenerative diseases represent a heterogeneous group of disorders that share
common features like abnormal protein aggregation, perturbed Ca2+ homeostasis …

Effective management and treatment of cancer depend on developing novel antitumor drugs
with the capability of targeting various molecular pathways. Identification and subsequent …

Currently, the majority of cell-based studies on neurodegeneration are carried out on two-
dimensional cultured cells that do not represent the cells residing in the complex …

The nucleolus is a stress sensor and compromised nucleolar activity may be considered as
an attractive anticancer strategy. In the present study, the effects of three plant-derived …

Neurodegenerative diseases are driven by several mechanisms such as inflammation,
abnormal protein aggregation, excitotoxicity, mitochondrial dysfunction and oxidative stress …

Neuroinflammation, which is mainly triggered by microglia, is a key contributor to multiple
neurodegenerative diseases. Natural products, and in particular Cannabis sativa L., due to …

Amniotic fluid stem cells (AFSCs) are characterized in vivo by a unique niche guarantying
their homeostatic role in the body. Maintaining the functionality of stem cells ex vivo for …