[HTML][HTML] Therapeutic host-directed strategies to improve outcome in tuberculosis
Abstract Bacille Calmette-Guérin (BCG) is the only licenced tuberculosis (TB) vaccine, but
has limited efficacy against pulmonary TB disease development and modest protection …
has limited efficacy against pulmonary TB disease development and modest protection …
Initial immune response after exposure to Mycobacterium tuberculosis or to SARS-COV-2: similarities and differences
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …
Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung
T cell immunity is essential for the control of tuberculosis (TB), an important disease of the
lung, and is generally studied in humans using peripheral blood cells. Mounting evidence …
lung, and is generally studied in humans using peripheral blood cells. Mounting evidence …
[HTML][HTML] Cytokine storm in tuberculosis and IL-6 involvement
FG Boni, I Hamdi, LM Koundi, K Shrestha… - Infection, Genetics and …, 2022 - Elsevier
Tuberculosis is probably the most seasoned illness of the humanity. Intricacies or
subsequent death emerging from these infections are frequently connected with cytokine …
subsequent death emerging from these infections are frequently connected with cytokine …
Cytokine upsurge among drug-resistant tuberculosis endorse the signatures of hyper inflammation and disease severity
P Sampath, A Rajamanickam, K Thiruvengadam… - Scientific Reports, 2023 - nature.com
Tuberculosis (TB) elimination is possible with the discovery of accurate biomarkers that
define the stages of infection. Drug-resistant TB impair the current treatment strategies and …
define the stages of infection. Drug-resistant TB impair the current treatment strategies and …
Identification of immune biomarkers in recent active pulmonary tuberculosis
Tuberculosis (TB) has remained an unsolved problem and a major public health issue,
particularly in developing countries. Pakistan is one of the countries with the highest …
particularly in developing countries. Pakistan is one of the countries with the highest …
Randomized trial of metformin with anti-tuberculosis drugs for early sputum conversion in adults with pulmonary tuberculosis
C Padmapriydarsini, M Mamulwar… - Clinical Infectious …, 2022 - academic.oup.com
Background Metformin, by reducing intracellular Mycobacterium tuberculosis growth, can be
considered an adjunctive therapy to anti-tuberculosis treatment (ATT). We determined …
considered an adjunctive therapy to anti-tuberculosis treatment (ATT). We determined …
Superinfection with SARS-CoV-2 has deleterious effects on Mycobacterium bovis BCG immunity and promotes dissemination of Mycobacterium tuberculosis
RE Hildebrand, SS Chandrasekar, M Riel… - Microbiology …, 2022 - Am Soc Microbiol
An estimated one-third of the world's population is infected with Mycobacterium tuberculosis,
with the majority being vaccinated with Mycobacterium bovis BCG. Severe acute respiratory …
with the majority being vaccinated with Mycobacterium bovis BCG. Severe acute respiratory …
Ghrelin as an anti-inflammatory and protective agent in ischemia/reperfusion injury
K Raghay, R Akki, D Bensaid, M Errami - Peptides, 2020 - Elsevier
Abstract Ischemia/reperfusion (I/R) continue to be the most frequent cause of damaged
tissues. Injured tissues resulted from the first ischemic insult, which is determined by the …
tissues. Injured tissues resulted from the first ischemic insult, which is determined by the …
Plasma chemokines are biomarkers of disease severity, higher bacterial burden and delayed sputum culture conversion in pulmonary tuberculosis
Plasma cytokines are biomarkers of disease extent and mycobacterial burden in pulmonary
tuberculosis (PTB). Whether chemokines can perform the same role in PTB is not known. We …
tuberculosis (PTB). Whether chemokines can perform the same role in PTB is not known. We …