Bacteria that readily adapt to different natural environments, can also exploit this versatility
upon infection of the host to persist. Pseudomonas aeruginosa, a ubiquitous Gram-negative …

Abstract The Gram-negative bacterium Pseudomonas aeruginosa uses a complex type III
secretion apparatus to inject effector proteins into host cells. The configuration of this …

▪ Abstract The role of biofilms in the pathogenesis of some chronic human infections is now
widely accepted. However, the criteria used to determine whether a given infection is …

SUMMARY A select group of microorganisms inhabit the airways of individuals with cystic
fibrosis. Once established within the pulmonary environment in these patients, many of …

Pseudomonas aeruginosa is an opportunistic pathogen, mainly affecting severe patients,
such as those in intensive care units (ICUs). High levels of antibiotic resistance and a long …

Diversity generally protects communities from unstable environmental conditions. This
principle, known as the “insurance hypothesis,” has been tested in many different …

Pseudomonas aeruginosa strains exhibit significant variability in pathogenicity and
ecological flexibility. Such interstrain differences reflect the dynamic nature of the P …

Contact lens wear is a common predisposing factor in microbial keratitis and is one of the
two preventable risk factors for corneal infection in a working age population. Our …

The genus Pseudomonas consists of more than 120 species that are ubiquitous in moist
environments such as water and soil ecosystems and are pathogenic to animals and …

Using a large multicenter prospective cohort of Pseudomonas aeruginosa bacteremia, we
demonstrate that the exoU type III secretion system genotype is independently associated …