Intracranial atherosclerotic stenosis: risk factors, diagnosis, and treatment

J Gutierrez, TN Turan, BL Hoh… - The Lancet Neurology, 2022 - thelancet.com
Intracranial atherosclerotic stenosis (ICAS) is one of the most frequent causes of stroke
worldwide and confers one of the greatest risks of recurrent stroke compared with other …

Large vessel occlusion stroke due to intracranial atherosclerotic disease: identification, medical and interventional treatment, and outcomes

A De Havenon, OO Zaidat, S Amin-Hanjani… - Stroke, 2023 - Am Heart Assoc
Large vessel occlusion stroke due to underlying intracranial atherosclerotic disease (ICAD-
LVO) is prevalent in 10 to 30% of LVOs depending on patient factors such as vascular risk …

Comparison of drug-eluting stent with bare-metal stent in patients with symptomatic high-grade intracranial atherosclerotic stenosis: a randomized clinical trial

B Jia, X Zhang, N Ma, D Mo, F Gao, X Sun… - JAMA …, 2022 - jamanetwork.com
Importance In-stent restenosis (ISR) is the primary reason for stroke recurrence after
intracranial stenting in patients who were treated with a standard bare-metal stent (BMS) …

[HTML][HTML] EHA guidelines on management of antithrombotic treatments in thrombocytopenic patients with cancer

A Falanga, A Leader, C Ambaglio, Z Bagoly… - …, 2022 - journals.lww.com
In cancer patients, thrombocytopenia can result from bone marrow infiltration or from
anticancer medications and represents an important limitation for the use of antithrombotic …

Apathy in small vessel cerebrovascular disease is associated with deficits in effort-based decision making

Y Saleh, C Le Heron, P Petitet, M Veldsman, D Drew… - Brain, 2021 - academic.oup.com
Patients with small vessel cerebrovascular disease frequently suffer from apathy, a
debilitating neuropsychiatric syndrome, the underlying mechanisms of which remain to be …

Intracranial arterial stenosis in Caucasian versus Chinese patients with TIA and minor stroke: two contemporaneous cohorts and a systematic review

X Leng, R Hurford, X Feng, KL Chan… - Journal of Neurology …, 2021 - jnnp.bmj.com
Background Intracranial arterial stenosis (ICAS) is an important cause of stroke worldwide.
Separate reports in Caucasians and Asians with stroke/transient ischaemic attack (TIA) have …

Effect of atherosclerosis on 5-year risk of major vascular events in patients with transient ischaemic attack or minor ischaemic stroke: An international prospective …

PC Lavallée, H Charles, GW Albers, LR Caplan… - The Lancet …, 2023 - thelancet.com
Background The prevalence of atherosclerosis and the long-term risk of major vascular
events in people who have had a transient ischaemic attack or minor ischaemic stroke …

RAGE-mediated T cell metabolic reprogramming shapes T cell inflammatory response after stroke

Y Zhang, F Li, C Chen, Y Li, W Xie… - Journal of Cerebral …, 2022 - journals.sagepub.com
The metabolic reprogramming of peripheral CD4+ T cells that occurs after stroke can lead to
imbalanced differentiation of CD4+ T cells, including regulation of T cells, and presents a …

From blood to brain: blood cell-based biomimetic drug delivery systems

YJ Li, JY Wu, J Liu, X Qiu, W Xu, T Tang, DX Xiang - Drug delivery, 2021 - Taylor & Francis
Brain drug delivery remains a major difficulty for several challenges including the blood–
brain barrier, lesion spot targeting, and stability during circulation. Blood cells including …

Identification of high-risk intracranial plaques with 3D high-resolution magnetic resonance imaging-based radiomics and machine learning

H Li, J Liu, Z Dong, X Chen, C Zhou, C Huang, Y Li… - Journal of …, 2022 - Springer
Background Identifying high-risk intracranial plaques is significant for the treatment and
prevention of stroke. Objective To develop a high-risk plaque model using three …