Spironolactone reversed hepato-ovarian triglyceride accumulation caused by letrozole-induced polycystic ovarian syndrome: tissue uric acid—a familiar foe

OA Adeyanju, TO Falodun, OS Michael… - Naunyn-Schmiedeberg's …, 2020 - Springer
Polycystic ovarian syndrome (PCOS) is a complex endocrine disease among women of
reproductive age and is one of the main causes of infertility. Non-alcoholic fatty liver disease …

Mineralocorticoid receptor blockade with finerenone improves heart function and exercise capacity in ovariectomized mice

M Pieronne‐Deperrois, A Guéret, Z Djerada… - ESC heart …, 2021 - Wiley Online Library
Aims In post‐menopausal women, incidence of heart failure with preserved ejection fraction
is higher than in men. Hormonal replacement therapies did not demonstrate benefits. We …

Effectiveness of Spironolactone in Reducing Osteoporosis and Future Fracture Risk in Middle-Aged and Elderly Hypertensive Patients

S Song, X Cai, J Hu, Q Zhu, D Shen, H Ma… - Drug Design …, 2024 - Taylor & Francis
Objective While the role of aldosterone in bone metabolism is well established, the specific
effects of the widely used aldosterone antagonist, spironolactone, on bone health are not …

[PDF][PDF] 雌激素受体β 在多种疾病中的生物学功能及机制

李从文, 魏云林 - 生命科学, 2019 - lifescience.sinh.ac.cn
雌激素受体β (estrogen receptor β, ERβ) 是经典的核受体, 属于核受体超家族成员.
在体内起着重要的生物学作用, 参与众多生理和病理活动, 是多种癌症, 心血管疾病, 肥胖症 …

Sex-Based Differences in Obesity, Gut Dysbiosis and Intestinal Inflammation in High-Fat Diet Mice

H Brettle - 2020 - opal.latrobe.edu.au
Sex-Based Differences in Obesity, Gut Dysbiosis and Intestinal Inflammation in High-Fat
Diet Mice. Page 1 i Sex-Based Differences in Obesity, Gut Dysbiosis and Intestinal …