Many large protein-nucleic acid complexes exhibit allosteric regulation. In these systems,
the propagation of the allosteric signaling is strongly coupled to conformational dynamics …

Allostery is a ubiquitous biological mechanism in which a distant binding site is coupled to
and drastically alters the function of a catalytic site in a protein. Allostery provides a high …

We propose high-order hypergraph walks as a framework to generalize graph-based
network science techniques to hypergraphs. Edge incidence in hypergraphs is quantitative …

Centrality metrics have been studied in the network science research. They have been used
in various networks, such as communication, social, biological, geographic, or contact …

Betweenness centrality (BC) is widely used to identify critical nodes in a network by
exploring the ability of all nodes to act as intermediaries for information exchange. However …

Surgery is a therapeutic option for people with epilepsy whose seizures are not controlled by
anti-epilepsy drugs. In pre-surgical planning, an array of data modalities, often including …

Code clone detection is an important research problem that has attracted wide attention in
software engineering. Many methods have been proposed for detecting code clone, among …

Identifying the most influential nodes in networked systems is of vital importance to optimize
their function and control. Several scalar metrics have been proposed to that effect, but the …

Malware scanning of an app market is expected to be scalable and effective. However,
existing approaches use either syntax-based features which can be evaded by …

Many biological processes are regulated by allosteric mechanisms that communicate with
distant sites in the protein responsible for functionality. The binding of a small molecule at an …