Proteins are nature's primary building blocks for the construction of sophisticated molecular
machines and dynamic materials, ranging from protein complexes such as photosystem II …

BACKGROUND Initially identified for their capability to induce heterotopic bone formation,
bone morphogenetic proteins (BMPs) are multifunctional growth factors that belong to the …

Electron microscopy (EM) achieves the highest spatial resolution in protein localization, but
specific protein EM labeling has lacked generally applicable genetically encoded tags for in …

Sáez, Juan C., Viviana M. Berthoud, María C. Brañes, Agustín D. Martínez, and Eric C.
Beyer. Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions …

Cells in tissues share ions, second messengers, and small metabolites through clusters of
intercellular channels called gap junctions. This type of intercellular communication permits …

Pannexins, a class of membrane channels, bear significant sequence homology with the
invertebrate gap junction proteins, innexins, and more distant similarities in their membrane …

We describe a general approach to designing two-dimensional (2D) protein arrays mediated
by noncovalent protein-protein interfaces. Protein homo-oligomers are placed into one of the …

The lens is an avascular organ suspended between the aqueous and vitreous humors of the
eye. The cellular structure is symmetric about an axis passing through its anterior and …

Cells in organs and tissues, it is now well established, make permeable junctions that
provide a path for direct flow of molecules between cell interiors. Ever since the nearly …

Gap junctions establish direct pathways for cells to transfer metabolic and electrical
messages. The local lipid environment is known to affect the structure, stability and …