Sepsis is characterised by a dysregulated host immune response to infection. Despite
recognition of its significance, immune status monitoring is not implemented in clinical …

Immune Modulation in Sepsis, ARDS, and Covid-19 — The Road Traveled and the Road Ahead
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Background Sustained yet intractable immunosuppression is commonly observed in septic
patients, resulting in aggravated clinical outcomes. However, due to the substantial …

Background & Aims The liver plays crucial roles in the regulation of immune defense during
acute systemic infections. However, the roles of liver cellular clusters and intercellular …

Maternal immune activation (MIA) during critical windows of gestation is correlated with long-
term neurodevelopmental deficits in the offspring, including increased risk for autism …

Background Sepsis is a life-threatening organ dysfunction caused by abnormal immune
responses to various, predominantly bacterial, infections. Different bacterial infections lead …

Liver, as an immune and detoxification organ, represents an important line of defense
against bacteria and infection and a vulnerable organ that is easily injured during sepsis …

Background Gut microbiota alterations have been implicated in sepsis and related infectious
diseases, but the causal relationship and underlying mechanisms remain unclear. Methods …

Background To identify differentially expressed lipid metabolism-related genes (DE-LMRGs)
responsible for immune dysfunction in sepsis. Methods The lipid metabolism-related hub …

Background The poor prognosis of sepsis warrants the investigation of biomarkers for
predicting the outcome. Several studies have indicated that PANoptosis exerts a critical role …