Production of multiple cell‐laden microtissue spheroids with a biomimetic hepatic‐lobule‐like structure

G Hong, J Kim, H Oh, S Yun, CM Kim… - Advanced …, 2021 - Wiley Online Library
The construction of an in vitro 3D cellular model to mimic the human liver is highly desired
for drug discovery and clinical applications, such as patient‐specific treatment and cell …

Microfluidic diamagnetic water-in-water droplets: a biocompatible cell encapsulation and manipulation platform

M Navi, N Abbasi, M Jeyhani, V Gnyawali, SSH Tsai - Lab on a Chip, 2018 - pubs.rsc.org
Droplet microfluidics enables cellular encapsulation for biomedical applications such as
single-cell analysis, which is an important tool used by biologists to study cells on a single …

Polymer-salt aqueous two-phase system (ATPS) micro-droplets for cell encapsulation

M Mastiani, N Firoozi, N Petrozzi, S Seo, M Kim - Scientific Reports, 2019 - nature.com
Biosample encapsulation is a critical step in a wide range of biomedical and bioengineering
applications. Aqueous two-phase system (ATPS) droplets have been recently introduced …

One-step generation and purification of cell-encapsulated hydrogel microsphere with an easily assembled microfluidic device

T Zhang, H Zhang, W Zhou, K Jiang, C Liu… - … in Bioengineering and …, 2022 - frontiersin.org
Cell-laden hydrogel microspheres with uniform size show great potential for tissue repair
and drug screening applications. Droplet microfluidic systems have been widely used for the …

Quantitative study of droplet generation by pressure-driven microfluidic flows in a flow-focusing microdroplet generator

W Zeng, B Wang, H Chang, P Neužil - Physics of Fluids, 2024 - pubs.aip.org
To precisely control the size of droplets is of great importance for the applications of the
droplet microfluidics. In a flow-focusing microdroplet generator, the pressure-driven …

Microfluidically-generated encapsulated spheroids (μ-GELS): an all-aqueous droplet microfluidics platform for multicellular spheroids generation

J Kieda, S Appak-Baskoy, M Jeyhani… - ACS Biomaterials …, 2023 - ACS Publications
Spheroids are three-dimensional clusters of cells that serve as in vitro tumor models to
recapitulate in vivo morphology. A limitation of many existing on-chip platforms for spheroid …

High inertial microfluidics for droplet generation in a flow-focusing geometry

M Mastiani, S Seo, B Riou, M Kim - Biomedical Microdevices, 2019 - Springer
A numerical study of aqueous droplet generation in a high Reynolds (Re) number air flow
was performed in a microfluidic flow-focusing geometry. Droplet breakup mechanisms, flow …

Quantitative measurements of the somatic cell count of fat-free milk based on droplet microfluidics

W Zeng, H Fu - Journal of Materials Chemistry C, 2020 - pubs.rsc.org
Based on droplet microfluidics, we demonstrate a new method that can quantitatively
measure the somatic cell count (SCC) of fat-free milk. A T-junction microdroplet generator is …

Precise monodisperse droplet production in a flow-focusing microdroplet generator

W Zeng, H Fu - Chemical Engineering Research and Design, 2020 - Elsevier
To precisely control the size of droplets produced in a flow-focusing microdroplet generator,
the pressure-driven device is designed to control the flow rates of the fluids during the …

Microfluidic fabrication of monodisperse microcapsules for thermo-triggered release of liposoluble drugs

Y Wang, Y Li, J Gong, J Ma - Polymers, 2020 - mdpi.com
Here, we report a novel thermo-triggered-releasing microcapsule for liposoluble drug
delivery. Monodisperse microcapsules with a poly (N-isopropylacrylamide-co-methacrylic …