Utrophin is an autosomal paralogue of dystrophin, a protein whose deficit causes Duchenne
and Becker muscular dystrophies (DMD/BMD). Utrophin is naturally overexpressed at the …

Duchenne muscular dystrophy (DMD) represents one of the most devastating types of
muscular dystrophies which affect boys already at early childhood. Despite the fact that the …

Sarcopenia is characterized of muscle mass loss and functional decline in elder individuals
which severely affects human physical activity, metabolic homeostasis, and life quality …

As a diverse and abundant class of endogenous RNAs, circular RNAs (circRNAs) participate
in processes including cell proliferation and apoptosis. Nevertheless, few researchers have …

In Duchenne muscular dystrophy (DMD), the activation of proinflammatory and metabolic
cellular pathways in skeletal muscle cells is an inherent characteristic. Synthetic …

Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD), which
represent the range of dystrophinopathies, account for nearly 80% of muscle dystrophy …

Upregulation of endogenous utrophin offers great promise for treating DMD, as it can
functionally compensate for the lack of dystrophin caused by DMD gene mutations, without …

microRNAs (miRNAs) are small non-coding RNAs required for the post-transcriptional
control of gene expression. MicroRNAs play a critical role in modulating muscle …

Our objective was to investigate the potential of three microRNAs, miR-181a-5p, miR-30c-
5p, and miR-206 as prognostic biomarkers for long-term follow up of Duchenne muscular …

Noncoding RNAs (ncRNAs), such as miRNAs and long noncoding RNAs, are key regulators
of gene expression at the post-transcriptional level and represent promising therapeutic …