Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Invariant natural killer T cell subsets—more than just developmental intermediates

SH Krovi, L Gapin - Frontiers in immunology, 2018 - frontiersin.org
Invariant natural killer T (iNKT) cells are a CD1d-restricted T cell population that can respond
to lipid antigenic stimulation within minutes by secreting a wide variety of cytokines. This …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells

M Paolino, A Choidas, S Wallner, B Pranjic… - Nature, 2014 - nature.com
Tumour metastasis is the primary cause of mortality in cancer patients and remains the key
challenge for cancer therapy. New therapeutic approaches to block inhibitory pathways of …

Adaptive immunity maintains occult cancer in an equilibrium state

CM Koebel, W Vermi, JB Swann, N Zerafa, SJ Rodig… - Nature, 2007 - nature.com
The capacity of immunity to control and shape cancer, that is, cancer immunoediting, is the
result of three processes,,,,,,, that function either independently or in sequence: elimination …

Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46

T Walzer, M Bléry, J Chaix, N Fuseri… - Proceedings of the …, 2007 - National Acad Sciences
Natural killer (NK) cells contribute to a variety of innate immune responses to viruses, tumors
and allogeneic cells. However, our understanding of NK cell biology is severely limited by …

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice

W He, CJ Chen, CE Mullarkey, JR Hamilton… - Nature …, 2017 - nature.com
The aim of candidate universal influenza vaccines is to provide broad protection against
influenza A and B viruses. Studies have demonstrated that broadly reactive antibodies …

Characterization of transcriptional regulatory networks that promote and restrict identities and functions of intestinal innate lymphoid cells

M Pokrovskii, JA Hall, DE Ochayon, R Yi… - Immunity, 2019 - cell.com
Innate lymphoid cells (ILCs) promote tissue homeostasis and immune defense but also
contribute to inflammatory diseases. ILCs exhibit phenotypic and functional plasticity in …

Tissue-resident NK cells mediate ischemic kidney injury and are not depleted by anti–asialo-GM1 antibody

F Victorino, DK Sojka, KS Brodsky… - The Journal of …, 2015 - journals.aai.org
NK cells are innate lymphoid cells important for immune surveillance, identifying and
responding to stress, infection, and/or transformation. Whereas conventional NK (cNK) cells …

A discontinuous hammerhead ribozyme embedded in a mammalian messenger RNA

M Martick, LH Horan, HF Noller, WG Scott - Nature, 2008 - nature.com
Structured RNAs embedded in the untranslated regions (UTRs) of messenger RNAs can
regulate gene expression. In bacteria, control of a metabolite gene is mediated by the self …