Diabetes represents a major health problem, involving a severe imbalance of blood sugar
levels, which can disturb the nerves, eyes, kidneys, and other organs. Diabes management …

The Target-Based Virtual Screening approach is widely employed in drug development, with
docking or molecular dynamics techniques commonly utilized for this purpose. This …

Carbohydrates are abundant naturally occurring biomolecules that play essential roles in a
wide variety of biological processes. In this paper, we describe the synthesis of a series of …

The objective of this study was to explore the molecular targets and mechanism of Ile-Pro-
Pro (IPP) and Val-Pro-Pro (VPP) on regulating glucose metabolism in hepatic cells and their …

Heliotropium is a genus of the Boraginaceae family. Its members are used in many
traditional and folklore medicines to treat several ailments. Despite this widespread usage …

Cholera is a severe small intestine bacterial disease caused by consumption of water and
food contaminated with Vibrio cholera. The disease causes watery diarrhea leading to …

Acinetobacter baumannii is a nosocomial bacterial pathogen and is responsible for a wide
range of diseases including pneumonia, necrotizing fasciitis, meningitis, and sepsis. The …

Triple negative breast cancers (TNBC) are clinically heterogeneous but mostly aggressive
malignancies devoid of expression of the estrogen, progesterone, and HER2 (ERBB2 or …

Due to the growth in the incidence of diabetes mellitus throughout the world, the urgency in
the search for new safe and effective inhibitors of α-amylase and α-glucosidase is …

Antimicrobial resistance is the key threat to global health due to high morbidity and mortality.
The alteration of bacterial proteins, enzymatic degradation, and change of membrane …