[HTML][HTML] Stem cell therapy for neonatal hypoxic-ischemic encephalopathy: a systematic review of preclinical studies
I Serrenho, M Rosado, A Dinis, C M. Cardoso… - International Journal of …, 2021 - mdpi.com
Neonatal hypoxic-ischemic encephalopathy (HIE) is an important cause of mortality and
morbidity in the perinatal period. This condition results from a period of ischemia and …
morbidity in the perinatal period. This condition results from a period of ischemia and …
Brain oxidative damage in murine models of neonatal hypoxia/ischemia and reoxygenation
I Torres-Cuevas, M Corral-Debrinski… - Free Radical Biology and …, 2019 - Elsevier
The brain is one of the main organs affected by hypoxia and reoxygenation in the neonatal
period and one of the most vulnerable to oxidative stress. Hypoxia/ischemia and …
period and one of the most vulnerable to oxidative stress. Hypoxia/ischemia and …
Insulin-producing cells from bone marrow stem cells versus injectable insulin for the treatment of rats with type I diabetes
Recently, stem cells have been considered renewable cell sources in the treatment of
diabetes and the development of insulin-producing cells. In this regard, the current study …
diabetes and the development of insulin-producing cells. In this regard, the current study …
[HTML][HTML] Intranasally administered exosomes from umbilical cord stem cells have preventive neuroprotective effects and contribute to functional recovery after perinatal …
G Thomi, M Joerger-Messerli, V Haesler, L Muri… - Cells, 2019 - mdpi.com
Perinatal brain injury (PBI) in preterm birth is associated with substantial injury and
dysmaturation of white and gray matter, and can lead to severe neurodevelopmental deficits …
dysmaturation of white and gray matter, and can lead to severe neurodevelopmental deficits …
[HTML][HTML] Intra-vital imaging of mesenchymal stromal cell kinetics in the pulmonary vasculature during infection
CH Masterson, A Tabuchi, G Hogan, G Fitzpatrick… - Scientific reports, 2021 - nature.com
Mesenchymal stem/stromal cells (MSCs) have demonstrated efficacy in pre-clinical models
of inflammation and tissue injury, including in models of lung injury and infection. Rolling …
of inflammation and tissue injury, including in models of lung injury and infection. Rolling …
Intravenously delivered multilineage-differentiating stress enduring cells dampen excessive glutamate metabolism and microglial activation in experimental perinatal …
Perinatal hypoxic ischemic encephalopathy (HIE) results in serious neurological dysfunction
and mortality. Clinical trials of multilineage-differentiating stress enduring cells (Muse cells) …
and mortality. Clinical trials of multilineage-differentiating stress enduring cells (Muse cells) …
[HTML][HTML] Optimizing stem cell therapy after ischemic brain injury
Stem cells have been used for regenerative and therapeutic purposes in a variety of
diseases. In ischemic brain injury, preclinical studies have been promising, but have failed …
diseases. In ischemic brain injury, preclinical studies have been promising, but have failed …
[HTML][HTML] Dedifferentiated fat cells administration ameliorates abnormal expressions of fatty acids metabolism-related protein expressions and intestinal tissue damage …
H Mimatsu, A Onoda, T Kazama, K Nishijima… - Scientific reports, 2023 - nature.com
Neonatal necrotizing enterocolitis (NEC) is a serious disease of premature infants that
necessitates intensive care and frequently results in life-threatening complications and high …
necessitates intensive care and frequently results in life-threatening complications and high …
[HTML][HTML] Aggregation of human mesenchymal stromal cells eliminates their ability to suppress human T cells
Mesenchymal stromal cells (MSCs) are administered locally to treat sites of inflammation.
Local delivery is known to cause MSCs to aggregate into “spheroids,” which alters gene …
Local delivery is known to cause MSCs to aggregate into “spheroids,” which alters gene …
[HTML][HTML] The enhancement of CCL2 and CCL5 by human bone marrow-derived mesenchymal stem/stromal cells might contribute to inflammatory suppression and …
K Yagura, H Ohtaki, T Tsumuraya, A Sato… - PLoS …, 2020 - journals.plos.org
Human bone marrow-derived mesenchymal stem/stromal cells (hMSCs) have shown
potential in facilitating recovery from spinal cord injury (SCI) through communicating with …
potential in facilitating recovery from spinal cord injury (SCI) through communicating with …