Enhancer of zeste homologue 2 (EZH2), the catalytic subunit of Polycomb repressive
complex 2 (PRC2), has attracted broad research attention in the past few years because of …

Abstract Polycomb group (PcG) and Trithorax group (TrxG) genes encode important
regulators of development and differentiation in metazoans. These two groups of genes …

Animal embryos need to specify different cell types, and the genetic functions that provide
such controls are easy to comprehend since they result in the formation of overtly …

THE amiloride-sensitive epithelial sodium channel constitutes the rate-limiting step for
sodium reabsorption in epithelial cells that line the distal part of the renal tubule, the distal …

We describe the effects of four recessive homeotic mutations that specifically disrupt the
development of flowers in Arabidopsis thaliana. Each of the recessive mutations affects the …

Organization and Evolution of Hox/HOM-C Complexes The genomic structural and
organizational similarities between vertebrate Hox and Drosophila HOM-C complexes …

Cellular memory is provided by two counteracting groups of chromatin proteins termed
Trithorax group (TrxG) and Polycomb group (PcG) proteins. TrxG proteins activate …

Hox genes encode a family of transcriptional regulators that elicit distinct developmental
programmes along the head-to-tail axis of animals. The specific regional functions of …

The enteric nervous system (ENS) is derived from both the vagal and sacral component of
the neural crest (NC). Here, we present the derivation of sacral ENS precursors from human …

The region-specific homeotic gene fork head (fkh) promotes terminal as opposed to
segmental development in the Drosophila embryo. We have cloned the f&h region by …