Metabolic diseases and their complications impose health and economic burdens
worldwide. Evidence from past experimental studies and clinical trials suggests our body …

Diabetic cognitive impairment (DCI) is a complex complication of diabetes in the central
nervous system, and its pathological mechanism is still being explored. Astrocytes are …

Importance Little is known about the associations of strict blood pressure (BP) control with
microstructural changes in small vessel disease markers. Objective To investigate the …

Importance Little is known about structural brain changes in type 1 diabetes (T1D) and
whether there are early manifestations of a neurodegenerative condition like Alzheimer …

Aims/hypothesis Chronic hyperglycaemia and recurrent hypoglycaemia are independently
associated with accelerated cognitive decline in type 1 diabetes. Recurrent hypoglycaemia …

OBJECTIVE To evaluate associations between plasma biomarkers of brain injury and MRI
and cognitive measures in participants with type 1 diabetes (T1D) from the Diabetes Control …

Background People living with type 1 diabetes (PWT1D) are at increased risk for
impairments in brain function, which may impact on daily life. Cognitive impairments in …

Over the past decades, life expectancy of people with type 1 diabetes has increased
considerably, which brings potential challenges due to the process of aging. Cognitive aging …

Background: Brain waves during sleep are involved in sensing and regulating peripheral
glucose level. Whether brain waves in patients with diabetes differ from those of healthy …

A significant metabolic illness known as diabetes mellitus is characterized by a lack of
insulin or the pancreas failure to produce enough insulin. The blood glucose levels rise as a …