Drug resistance is a major challenge in breast cancer (BC) treatment at present.
Accumulating studies indicate that breast cancer stem cells (BCSCs) are responsible for the …

Mesenchymal stromal cells (MSCs) are heterogeneous and contain several populations,
including stem cells. MSCs' secretome has the ability to induce proliferation, differentiation …

Allogeneic hematopoietic cell transplantation (HCT) is a potentially curative therapy for
patients with a variety of malignant and non-malignant diseases. Despite its life-saving …

Simple Summary Increasing number of cancer patients and significant mortality among
these patients are attributed to many factors including anticancer drug resistance. Among a …

Intended to explore synthetic lethality and develop better combinatorial regimens, we
screened colorectal cancer (CRC) cells using poly ADP-ribose (PAR) polymerase (PARP) …

Chemotherapeutic agents are part of the standard treatment algorithms for many
malignancies; however, their application and dosage are limited by their toxic effects to …

Mesenchymal stem cells (MSCs) are an integral part of the bone marrow niche and aid in
the protection, regeneration and proliferation of hematopoietic stem cells after exposure to …

Mesenchymal stem cells (MSCs) have been shown to attenuate pulmonary damage induced
by bleomycin-based anticancer treatments, but the influence of bleomycin on the stem cells …

Abstract Background Mesenchymal stem cells (MSCs) participate in the regeneration of
tissue lesions induced by antimetabolite chemotherapy; however, the influence of this class …

Chemotherapy constitutes one of the key treatment modalities for solid and hematological
malignancies. Albeit being an effective treatment, chemotherapy application is often limited …