Quinoline-based antimalarial hybrid compounds

S Vandekerckhove, M D'hooghe - Bioorganic & medicinal chemistry, 2015 - Elsevier
Quinoline-containing compounds, such as quinine and chloroquine, have a long-standing
history as potent antimalarial agents. However, the increasing resistance of the Plasmodium …

Rhodanine as a privileged scaffold in drug discovery

T Tomasic, LP Masic - Current Medicinal Chemistry, 2009 - ingentaconnect.com
Rhodanines, thiazolidine-2, 4-diones and pseudothiohydantoins have become a very
interesting class of heterocyclic compounds since the introduction of various glitazones and …

Simultaneous improvement of antimicrobial, antifouling, and transport properties of forward osmosis membranes with immobilized highly-compatible polyrhodanine …

A Rahimpour, SF Seyedpour… - … science & technology, 2018 - ACS Publications
This work shows that incorporating highly compatible polyrhodanine nanoparticles (PRh-
NPs) into a polyamide (PA) active layer allows for fabricating forward osmosis (FO) thin-film …

Thermal properties, antimicrobial activity and DNA binding of Ni (II) complexes of azo dye compounds

AZ El-Sonbati, MA Diab, SM Morgan - Journal of Molecular Liquids, 2017 - Elsevier
A novel series of nickel (II) azo dye complexes of 5-(4-methoxyphenylazo)-2-thioxo-4-
thiazolidinone (HL 1), 5-(4-methylphenylazo)-2-thioxo-4-thiazolidinone (HL 2), 5 …

Polymer complexes. LXXI. Spectroscopic studies, thermal properties, DNA binding and antimicrobial activity of polymer complexes

MA Diab, AZ El‐Sonbati, SM Morgan… - Applied …, 2018 - Wiley Online Library
Polymer complexes of Co (II), Ni (II), Mn (II), Cr (III) and Cd (II) were prepared by the reaction
of 3‐allyl‐5‐[(4‐nitrophenylazo)]‐2‐thioxothiazolidine‐4‐one (HL) with metal ions. The …

Drug screening of rhodanine derivatives for antibacterial activity

S Maddila, S Gorle… - Expert Opinion on Drug …, 2020 - Taylor & Francis
Introduction: Bacteriological infections are a major risk to human health. These include all
hospital and public-acquired infections. In drug discovery, rhodanines are privileged …

Synthesis and evaluation of some new fluorinated hydroquinazoline derivatives as antifungal agents

MM Ghorab, SM Abdel-Gawad, MSA El-Gaby - Il Farmaco, 2000 - Elsevier
The key intermediate octahydroquinazoline (1) was obtained in one pot synthesis by a
modification of the Biginelli reaction. Compound 1 was allowed to react with phenacyl …

Synthesis, molecular geometry, spectroscopic studies and thermal properties of Co (II) complexes

SM Morgan, MA Diab… - Applied Organometallic …, 2018 - Wiley Online Library
Co (II) complexes (1‐4) were prepared and characterized by elemental analyses, infrared
spectra, spectral studies, magnetic susceptibility measurements, X‐ray diffraction analysis …

Synthesis, spectroscopic, thermal properties, Calf thymus DNA binding and quantum chemical studies of M (II) complexes

SM Morgan, MA Diab… - Applied Organometallic …, 2018 - Wiley Online Library
A new series of transition metal complexes of Cu (II), Co (II), Ni (II), Mn (II) and Cd (II) were
prepared from the ligand of 5‐(4‐benzenesulfonic acid azo)‐2‐thioxo‐4‐thiazolidinone …

Influence of substituent effects on spectroscopic properties and antimicrobial activity of 5-(4′-substituted phenylazo)-2-thioxothiazolidinone derivatives

MI Abou-Dobara, AZ El-Sonbati, SM Morgan - World Journal of …, 2013 - Springer
Abstract 5-(4′-substituted phenylazo)-2-thioxothiazolidinone derivatives (HL n) have been
synthesized and characterized by elemental analysis, spectra (IR, electronic and 1 H NMR) …