The development of thrombotic disorders in humans is one of the most common causes of
morbidity and mortality in the Western world. Thrombotic disease can be classified in broad …

Ischaemic stroke can be caused by a number of monogenic disorders, and in such cases
stroke is frequently part of a multisystem disorder. Cerebral autosomal dominant arteriopathy …

Background: The prevalence of duodenal carcinoma is much higher in familial
adenomatous polyposis (FAP) than in the background population, and duodenal …

Ischemic stroke is thought to have a polygenic basis, but identification of stroke susceptibility
genes and quantification of associated risks have been hampered by conflicting results from …

The central importance of platelets in the development of arterial thrombosis and
cardiovascular disease is well established. No other single cell type is responsible for as …

Arterial thrombosis is a complex disorder that involves multiple genetic and environmental
factors interacting to produce the characteristic phenotype. In the past decades, investigators …

It has long been thought that an individual thrombotic tendency increases the risk of
myocardial infarction, especially in young adults. Several “prothrombotic” genetic factors that …

The removal of albumin and other high abundance proteins is a routine first step in the
analysis of serum and plasma proteomes. However, as albumin can bind proteins and …

Background and Purpose—A number of studies have examined the relationship between
genetic platelet glycoprotein variants and early-onset atherothrombotic disease, particularly …

The present study aimed to assess the association of 16 polymorphisms in genes encoding
prothrombotic and cardiovascular risk factors with COVID‐19 disease severity: FV G1691A …