Analytical methods for assessing antimicrobial activity of nanomaterials in complex media: advances, challenges, and perspectives

X Zhang, X Hou, L Ma, Y Shi, D Zhang, K Qu - Journal of …, 2023 - Springer
Assessing the antimicrobial activity of engineered nanomaterials (ENMs), especially in
realistic scenarios, is of great significance for both basic research and applications. Multiple …

Ganoderma lucidum polysaccharides inhibit in vitro tumorigenesis, cancer stem cell properties and epithelial-mesenchymal transition in oral squamous cell carcinoma

MR de Camargo, TF Frazon, KK Inacio… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance The polysaccharides of the millenary mushroom
Ganoderma lucidum (GL) have been shown for decades to present anti-tumor activities, but …

Automatically showing microbial growth kinetics with a high-performance microbial growth analyzer

X Zhang, Q Yang, L Ma, D Zhang, W Lin… - Biosensors and …, 2023 - Elsevier
It is difficult to show microbial growth kinetics online when they grow in complex matrices.
We presented a novel strategy to address this challenge by developing a high-performance …

Single-cell analysis reveals context-dependent, cell-level selection of mtDNA

AV Kotrys, TJ Durham, XA Guo, VR Vantaku, S Parangi… - Nature, 2024 - nature.com
Heteroplasmy occurs when wild-type and mutant mitochondrial DNA (mtDNA) molecules co-
exist in single cells. Heteroplasmy levels change dynamically in development, disease and …

Aglycone flavonoid brachydin A shows selective cytotoxicity and antitumoral activity in human metastatic prostate (DU145) cancer cells

LCB de Oliveira, HL Nunes, DL Ribeiro… - Cytotechnology, 2021 - Springer
In prostate cancer, flavonoids possess a wide variety of anticancer effects, focused on the
antioxidant/pro-oxidant activity, inactivation of the androgen receptor, cell cycle arrest …

P2X1 and P2X7 receptor overexpression is a negative predictor of survival in muscle-invasive bladder cancer

S Ledderose, S Rodler, L Eismann, G Ledderose… - Cancers, 2023 - mdpi.com
Simple Summary Bladder cancer is one of the most common malignancies. The prognosis is
particularly poor for advanced cancer. There is a need for new prognostic markers to guide …

Modelling and differential quantification of electric cell-substrate impedance sensing growth curves

ARD Binder, AN Spiess, MW Pfaffl - Sensors, 2021 - mdpi.com
Measurement of cell surface coverage has become a common technique for the assessment
of growth behavior of cells. As an indirect measurement method, this can be accomplished …

Bothrops moojeni snake venom induces an inflammatory response in preadipocytes: Insights into a new aspect of envenomation

R Maia-Marques, DS Teixeira… - PLoS neglected …, 2022 - journals.plos.org
Bothrops envenomation is a public health problem in Brazil. Despite the advances in the
knowledge of the pathogenesis of systemic and local effects induced by Bothrops venom …

Human macrophages and monocyte-derived dendritic cells stimulate the proliferation of endothelial cells through midkine production

EA Said, S Al-Dughaishi, W Al-Hatmi, I Al-Reesi… - Plos one, 2022 - journals.plos.org
The cytokine midkine (MK) is a growth factor that is involved in different physiological
processes including tissue repair, inflammation, the development of different types of cancer …

Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene

Z Novakova, M Milosevic, Z Kutil, M Ondrakova… - Scientific Reports, 2022 - nature.com
In humans, disruptions in the heme biosynthetic pathway are associated with various types
of porphyrias, including variegate porphyria that results from the decreased activity of …