Diabetic macroangiopathy: Pathogenetic insights and novel therapeutic approaches with focus on high glucose-mediated vascular damage

R Madonna, D Pieragostino, CR Balistreri, C Rossi… - Vascular …, 2018 - Elsevier
Diabetic macroangiopathy–a specific form of accelerated atherosclerosis–is characterized
by intra-plaque new vessel formation due to excessive/abnormal neovasculogenesis and …

The C1q/TNF-related proteins (CTRPs) in pathogenesis of obesity-related metabolic disorders: Focus on type 2 diabetes and cardiovascular diseases

M Shanaki, P Shabani, A Goudarzi, A Omidifar… - Life Sciences, 2020 - Elsevier
The growing evidence has been tried to explain and characterize C1q/TNF-related proteins
(CTRPs) family as the potential diagnostic or therapeutic targets of obesity-related metabolic …

[HTML][HTML] Circulating C1q complement/TNF-related protein (CTRP) 1, CTRP9, CTRP12 and CTRP13 concentrations in Type 2 diabetes mellitus: In vivo regulation by …

B Bai, B Ban, Z Liu, MM Zhang, BK Tan, J Chen - PloS one, 2017 - journals.plos.org
Objectives The C1q complement/TNF-related protein (CTRP) superfamily, which includes
the adipokine adiponectin, has been shown in animal models to have positive metabolic …

[HTML][HTML] CTRP1 aggravates cardiac dysfunction post myocardial infarction by modulating TLR4 in macrophages

Y Gu, X Hu, PB Ge, Y Chen, S Wu… - Frontiers in …, 2021 - frontiersin.org
CTRP1 (C1q/TNF-α [tumour necrosis factor-α]-related protein 1), an adiponectin paralog, is
associated with diabetes and adverse events in cardiovascular disease. However, its effect …

The effect of combined resistance aerobic exercise training on concentrations of asprosin and complement C1q tumor necrosis factor-related protein-1 in men with …

M Zarei, J Nakhzari Khodakheyr, A Rashidlamir… - Sport Sciences for …, 2021 - Springer
Aim The present study aimed to investigate the effect of combined resistance aerobic
exercise training on asprosin and complement C1q tumor necrosis factor-related protein-1 …

C1q/TNF-α–related protein 1 (CTRP1) maintains blood pressure under dehydration conditions

S Han, AL Jeong, S Lee, JS Park… - Circulation …, 2018 - Am Heart Assoc
Rationale: Circulating CTRP1 (C1q/TNF-α [tumor necrosis factor-α]–related protein 1) levels
are increased in hypertensive patients compared with those in healthy subjects …

[HTML][HTML] CTRP1 attenuates cerebral ischemia/reperfusion injury via the PERK signaling pathway

H Fei, P Xiang, W Luo, X Tan, C Gu, M Liu… - Frontiers in Cell and …, 2021 - frontiersin.org
Cerebral ischemic stroke is one of the leading causes of death worldwide. Previous studies
have shown that circulating levels of CTRP1 are upregulated in patients with acute ischemic …

C1q tumor necrosis factor related proteins (CTRPs) in patients with cardiovascular diseases

Z Barmoudeh, MH Shahraki… - Acta Biochimica …, 2023 - publish.kne-publishing.com
Cardiovascular diseases (CVDs) are the major cause of death in both developed and
developing countries. It is widely accepted that predicting CVDs in the early stages or before …

C1q/TNF-related protein 1, a multifunctional adipokine: an overview of current data

JD Janowska - The American Journal of the Medical Sciences, 2020 - Elsevier
The present review aimed to present the research highlights on C1q/TNF-related protein 1
(CTRP1), a member of the recently discovered family of highly conserved adiponectin …

[HTML][HTML] CTRP1 aggravates cardiac fibrosis by regulating the NOX2/P38 pathway in macrophages

C Li, S Ying, X Wu, T Zhu, Q Zhou, Y Zhang… - Cell Journal …, 2022 - ncbi.nlm.nih.gov
Objective C1q/TNF-related proteins 1 (CTRP1) is a recently identified adiponectin
associated with obesity-linked disorders and adverse cardiovascular events. The effect of …