What is needed to achieve effective and sustainable control of African animal trypanosomosis?
A welcome resurgence in African animal trypanosomosis (AAT) research has resulted in
advances in capabilities, foundational datasets, and understanding. Additionally, there is the …
advances in capabilities, foundational datasets, and understanding. Additionally, there is the …
[HTML][HTML] Animal Trypanosomiasis: Challenges and Prospects for New Vaccination Strategies
SH Pereira, FP Alves, SMR Teixeira - Microorganisms, 2024 - mdpi.com
Animal trypanosomiasis, such as nagana, surra, and dourine, represent a significant
challenge to animal health and economic development, especially in tropical and …
challenge to animal health and economic development, especially in tropical and …
[HTML][HTML] The activities of suaveolol and other compounds from Hyptis suaveolens and Momordica charantia against the aetiological agents of African trypanosomiasis …
EE Oaikhena, UA Yahaya, SM Abdulsalami… - Experimental …, 2024 - Elsevier
African trypanosomiasis and malaria are among the most severe health challenges to
humans and livestock in Africa and new drugs are needed. Leaves of Hyptis suaveolens …
humans and livestock in Africa and new drugs are needed. Leaves of Hyptis suaveolens …
Antitrypanosomal and antileishmanial activity of compounds from some Nigerian plants
S Alenezi, NP Igoli, AI Gray, EE Oaikhena… - Experimental …, 2024 - Elsevier
Ten compounds, six extracts and five fractions obtained from three Nigerian plants were
assayed for their in vitro antitrypanosomal and antileishmanial activities. Each plant was …
assayed for their in vitro antitrypanosomal and antileishmanial activities. Each plant was …
Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis
K Ilbeigi, D Mabille, A Matheeussen… - ACS Infectious …, 2024 - ACS Publications
African trypanosomiasis is a widespread disease of human and veterinary importance
caused by various Trypanosoma spp. with a globally devastating impact and a need for …
caused by various Trypanosoma spp. with a globally devastating impact and a need for …
[HTML][HTML] Clinical and epidemiological investigation of human infection with zoonotic parasite Trypanosoma dionisii in China
N Xu, X Zhang, H Liu, Y Xu, H Lu, L Zhao, Y He… - Journal of Infection, 2024 - Elsevier
Background Trypanosomiasis continues to pose a global threat to human health, with
human infection mainly caused by Trypanosoma brucei and Trypanosoma cruzi. Methods …
human infection mainly caused by Trypanosoma brucei and Trypanosoma cruzi. Methods …
Benign-by-Design SAHA Analogues for Human and Animal Vector-Borne Parasitic Diseases
M Rossi, B Martinengo, E Diamanti… - ACS Medicinal …, 2024 - ACS Publications
The search for new drugs fulfilling One Health and Green Chemistry requirements is an
urgent call. Here, for the first time, we envisaged developing SAHA analogues by starting …
urgent call. Here, for the first time, we envisaged developing SAHA analogues by starting …
Symbiotic bacteria Sodalis glossinidius, Spiroplasma sp and Wolbachia do not favour Trypanosoma grayi coexistence in wild population of tsetse flies collected in …
YM Mfopit, E Bilgo, S Boma, MB Somda, JE Gnambani… - BMC microbiology, 2024 - Springer
Background Tsetse flies, the biological vectors of African trypanosomes, have established
symbiotic associations with different bacteria. Their vector competence is suggested to be …
symbiotic associations with different bacteria. Their vector competence is suggested to be …
Molecular characterization of trypanocide-resistant strains derived from a single field isolate of Trypanosoma evansi
DT Subekti, Z Azmi, DA Kurniawati, LT Suwanti… - Veterinary …, 2024 - Elsevier
Abstract Four strains (SB-PR, SB-RS, SB-RD, and SB-RM) of Trypanosoma evansi (T.
evansi) were used in this study. SB-PR is known to be trypanocide-sensitive, while the …
evansi) were used in this study. SB-PR is known to be trypanocide-sensitive, while the …
[HTML][HTML] Environmental impacts of drugs against parasitic vector-borne diseases and the need to integrate sustainability into their development and use
Background The current scientific discourse on environmental impacts of veterinary
medicines mostly focuses on ectoparasiticides. Meanwhile, the environmental impacts of …
medicines mostly focuses on ectoparasiticides. Meanwhile, the environmental impacts of …