Bridging thrombolysis achieved better outcomes than direct thrombectomy after large vessel occlusion: an updated meta-analysis

Y Wang, X Wu, C Zhu, M Mossa-Basha, A Malhotra - Stroke, 2021 - Am Heart Assoc
The utility and necessity of pretreatment with intravenous thrombolysis (IVT) before
mechanical thrombectomy (MT) remains an issue of strong debate. This study aims to …

Direct mechanical thrombectomy without intravenous thrombolysis versus bridging therapy for acute ischemic stroke: a meta-analysis of randomized controlled trials

A Podlasek, PS Dhillon, W Butt… - … Journal of Stroke, 2021 - journals.sagepub.com
Background Direct mechanical thrombectomy may result in similar outcomes compared to a
bridging approach with intravenous thrombolysis (IVT+ MT) in acute ischemic stroke. Recent …

Direct mechanical thrombectomy in tPA-ineligible and-eligible patients versus the bridging approach: a meta-analysis

J Kaesmacher, P Mordasini, M Arnold… - Journal of …, 2019 - jnis.bmj.com
Background Whether pretreatment with intravenous thrombolysis prior to mechanical
thrombectomy (IVT+ MTE) adds additional benefit over direct mechanical thrombectomy …

Intravenous thrombolysis before mechanical thrombectomy for acute ischemic stroke: a meta‐analysis

H Du, H Lei, G Ambler, S Fang, R He… - Journal of the …, 2021 - Am Heart Assoc
Background Whether intravenous thrombolysis before mechanical thrombectomy provides
additional benefit for functional outcome in acute ischemic stroke remains uncertain. We …

The administration of rtPA before mechanical thrombectomy in acute ischemic stroke patients is associated with a significant reduction of the retrieved clot area but it …

R Rossi, S Fitzgerald, S Molina, OM Mereuta… - Journal of Thrombosis …, 2021 - Springer
Both intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) are evidence-
based treatments for acute ischemic stroke (AIS) in selected cases. Recanalization may …

Neutrophil dynamics and inflammaging in acute ischemic stroke: A transcriptomic review

TA Bui, GC Jickling, IR Winship - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Stroke is among the leading causes of death and disability worldwide. Restoring blood flow
through recanalization is currently the only acute treatment for cerebral ischemia …

Bridging versus direct mechanical thrombectomy in acute ischemic stroke: a subgroup pooled meta-analysis for time of intervention, eligibility, and study design

S Vidale, M Romoli, D Consoli… - Cerebrovascular Diseases, 2020 - karger.com
Abstract Background and Aim: The risk/benefit profile of intravenous thrombolysis (IVT) prior
to endovascular thrombectomy (EVT) in acute ischemic stroke is still unclear. We provide a …

Mechanical thrombectomy for acute ischemic stroke: considerations in children

LR Sun, D Harrar, G Drocton, C Castillo-Pinto… - Stroke, 2020 - Am Heart Assoc
The use of mechanical thrombectomy for the treatment of acute childhood arterial ischemic
stroke with large vessel occlusion is increasing, with mounting evidence for its feasibility and …

Risk of distal embolization from tPA (tissue-type plasminogen activator) administration prior to endovascular stroke treatment

AC Flint, AL Avins, A Eaton, S Uong, SP Cullen… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: In large artery occlusion stroke, both intravenous (IV) tPA (tissue-
type plasminogen activator) and endovascular stroke treatment (EST) are standard-of-care …

Intravenous thrombolysis before mechanical thrombectomy for acute ischemic stroke due to large vessel occlusion; should we cross that bridge? A systematic review …

HS Ghaith, M Elfil, MD Gabra, AA Nawar… - Neurological …, 2022 - Springer
Background The use of intravenous thrombolysis (IVT) before mechanical thrombectomy
(MT) for acute ischemic stroke due to large vessel occlusion (AIS-LVO) is a debatable …