[HTML][HTML] Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis

M Zhao, R Wang, K Yang, Y Jiang, Y Peng, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

The recent development of hybridization chain reaction strategies in biosensors

C Zhang, J Chen, R Sun, Z Huang, Z Luo, C Zhou… - ACS …, 2020 - ACS Publications
With the continuous development of biosensors, researchers have focused increasing
attention on various signal amplification strategies to pursue superior performance for more …

Electrochemiluminescence biosensor based on entropy-driven amplification and a tetrahedral DNA nanostructure for miRNA-133a detection

L Yu, L Zhu, M Yan, S Feng, J Huang… - Analytical …, 2021 - ACS Publications
The early and rapid diagnosis of acute myocardial infarction (AMI) is of great significance to
its treatment. Here, we developed an electrochemiluminescence biosensor based on an …

Sensitive and amplification-free electrochemiluminescence biosensor for HPV-16 detection based on CRISPR/Cas12a and DNA tetrahedron nanostructures

L Yu, Y Peng, M Sheng, Q Wang, J Huang, X Yang - ACS sensors, 2023 - ACS Publications
Rapid and accurate detection of biomarkers was very important for early screening and
treatment of diseases. Herein, a sensitive and amplification-free electrochemiluminescence …

Nucleic acid‐based electrochemical biosensor: Recent advances in probe immobilization and signal amplification strategies

K Thapa, W Liu, R Wang - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
With the increasing importance of accurate and early disease diagnosis and the
development of personalized medicine, DNA‐based electrochemical biosensor has …

Hybridization chain reaction and its applications in biosensing

J Wu, J Lv, X Zheng, ZS Wu - Talanta, 2021 - Elsevier
To pursue the sensitive and efficient detection of informative biomolecules for bioanalysis
and disease diagnosis, a series of signal amplification techniques have been put forward …

The TDs/aptamer cTnI biosensors based on HCR and Au/Ti3C2-MXene amplification for screening serious patient in COVID-19 pandemic

X Mi, H Li, R Tan, B Feng, Y Tu - Biosensors and Bioelectronics, 2021 - Elsevier
The accurate assay of cardiac troponin I (cTnI) is very important for acute myocardial
infarction (AMI), it also can be employed as an effective index for screening serious patients …

Zinc porphyrin/MXene hybrids with phosphate-induced stimuli-responsive behavior for dual-mode fluorescent/electrochemiluminescent ratiometric biosensing

H Sun, J Guan, H Chai, K Yu, L Qu, X Zhang… - Biosensors and …, 2024 - Elsevier
Highly sensitive ratiometric biosensors have attracted much attention in biomarker detection,
but most rely on single-mode signals, which can affect accuracy. The development of new …

Ferrocene-functionalized covalent organic frameworks and target catalyzed hairpin assembly strategy for amplified electrochemical determination of microRNAs

S Feng, Y Xue, J Huang, X Yang - Analytical Chemistry, 2022 - ACS Publications
MicroRNAs (miRNAs) are considered as significant biomarkers in early diagnosis and
treatment of diseases. Herein, an electrochemical biosensor that uses ferrocene (Fc) …

Self-powered DNAzyme walker enables dual-mode biosensor construction for electrochemiluminescence and electrochemical detection of microRNA

S Du, B Xie, H Gao, J Zhang, H Fu, F Liao… - Analytical …, 2023 - ACS Publications
Herein, an electrochemiluminescence (ECL) and electrochemical (EC) dual-mode
biosensor platform with a self-powered DNAzyme walking machine was established for …