The extracellular matrix (ECM) is an essential component of the heart that imparts
fundamental cellular processes during organ development and homeostasis. Most …

The permanent cellular constituents of the heart include cardiac fibroblasts, myocytes,
endothelial cells, and vascular smooth muscle cells. Previous studies have demonstrated …

The term matricellular proteins describes a family of structurally unrelated extracellular
macromolecules that, unlike structural matrix proteins, do not play a primary role in tissue …

The extracellular matrix (ECM) of the developing heart contains numerous molecules that
form a dynamic environment that plays an active and crucial role in the regulation of cellular …

Tissue development and homeostasis are dependent upon the concerted synthesis,
maintenance, and degradation of extracellular matrix (ECM) molecules. Cardiac fibrosis is …

Periostin, an extracellular matrix protein belonging to the fasciclin family, has been shown to
play a critical role in the process of remodeling during tissue/organ development or repair …

Periostin is a secretory protein with a multi-domain structure, comprising an amino-terminal
cysteine-rich EMI domain, four internal FAS 1 domains, and a carboxyl-terminal hydrophilic …

TBX3 is critical for human development: mutations in TBX3 cause congenital anomalies in
patients with ulnar-mammary syndrome. Data from mice and humans suggest multiple roles …

We previously reported that chronic rhinosinusitis with nasal polyps (CRSwNP) was
subdivided into four chronic rhinosinusitis (CRS) subtypes using the JESREC scoring …

Recent studies have placed an increasing amount of emphasis on the cardiovascular
system and understanding how the heart and its vasculature can be regenerated following …