Bioflavonoids are natural polyphenolic secondary metabolites that are medicinal. These
compounds possess antitumor, cardioprotective, anti-inflammatory, antimicrobial, antiviral …

Triple-negative breast cancer (TNBC) is a highly resistant, lethal, and metastatic sub-division
of breast carcinoma, characterized by the deficiency of estrogen receptor (ER), progesterone …

Lipid nanoparticles are used widely as anticancer drug and gene delivery systems.
Internalizing into the target cell is a prerequisite for the proper activity of many …

Great strides have been made in triple negative breast cancer (TNBC) treatment, which
represents 20% of total predicted annual US breast cancer (BC) cases. Despite the …

Flavonoids are a large group of polyphenols with numerous biological effects on cancer
cells. They have been shown to affect proliferation via cell cycle arrest, apoptosis and …

Estrogen receptors (ERs) are primarily expressed in cancer cells and interfere with the
epidermal growth factor (EGFR) signal pathway. However, data are limited regarding the …

Chalcones are direct precursors in the biosynthesis of flavonoids. They have an α, β-
unsaturated carbonyl system which gives them broad biological properties. Among the …

Despite a decline in overall incidence rates for cancer in the past decade, due in part to
impressive advancements in both diagnosis and treatment, breast cancer (BC) remains the …

Breast carcinoma disease is the most common ailment affecting women globally. Despite
relentless efforts by scientists, numerous scientific strategies have been blocked by the …

Background The aim of this study was to identify potential therapeutic target genes for breast
cancer (BC) by the investigation of gene expression changes after ionizing radiation (IR) in …