Fatty acids have received growing interest in Leishmania biology with the characterization of
the enzymes allowing the complete fatty acid synthesis of this trypanosomatid parasite. This …

Oxylipins, or oxygenated lipids, are universal signalling molecules across all kingdoms of
life. These molecules, either produced by microbial pathogens or their mammalian host …

Several species of Acanthamoeba genus are potential pathogens and etiological agents of
several diseases. The pathogenic mechanisms carried out by these amoebae in different …

Lipid droplets (LDs; lipid bodies) are intracellular sites of lipid storage and metabolism
present in all cell types. Eukaryotic LDs are involved in eicosanoid production during several …

This article provides a comprehensive review of several subclasses of metallo-type
peptidases expressed by the main clinically relevant protozoa, including Plasmodium spp …

In Leishmania mexicana, the protease gp63 has been documented as the protein
responsible for cyclooxygenase (COX) activity. The present work aimed to obtain a …

Highly dynamic ribosomes, glycogen granules, thinly fibrillar material, and multiple
membrane‐bound vesicles are embedded in the matrix‐rich cytoplasm of Entamoeba spp …

BACKGROUND The knowledge about eicosanoid metabolism and lipid droplet (LD)
formation in the Leishmania is very limited and new approaches are needed to identify …

Leishmaniasis is a disease caused by the protozoan parasite Leishmania known to affect
millions of individuals worldwide. In recent years, we have established the critical role …