News and views on ion channels in cancer: is cancer a channelopathy?
Ion channels are key signaling proteins found throughout the body; they are critical in many,
wide-ranging physiological processes, from gene expression, sensory perception and …
wide-ranging physiological processes, from gene expression, sensory perception and …
Trpv6 channel targeting using monoclonal antibody induces prostate cancer cell apoptosis and tumor regression
A Haustrate, C Cordier, G Shapovalov… - Cell Death & …, 2024 - nature.com
TRPV6 calcium channel is a prospective target in prostate cancer (PCa) since it is not
expressed in healthy prostate while its expression increases during cancer progression …
expressed in healthy prostate while its expression increases during cancer progression …
Characterization of the TRPV6 calcium channel-specific phenotype by RNA-seq in castration-resistant human prostate cancer cells
C Cordier, A Haustrate, N Prevarskaya… - Frontiers in …, 2023 - frontiersin.org
Background: Transient receptor potential vanilloid subfamily member 6 (TRPV6), a highly
calcium-selective channel, has been shown to play a significant role in calcium homeostasis …
calcium-selective channel, has been shown to play a significant role in calcium homeostasis …
Overexpression of TRPV6 Inhibits Coronary Atherosclerosis–Related Inflammatory Response and Cell Apoptosis via the PKA/UCP2 Pathway
L Zheng, H Zhang, X Li - Cardiovascular Therapeutics, 2024 - Wiley Online Library
Objective: This research is aimed at unravelling the intricate relationship between transient
receptor potential vanilloid 6 (TRPV6), protein kinase A (PKA), uncoupling protein 2 (UCP2) …
receptor potential vanilloid 6 (TRPV6), protein kinase A (PKA), uncoupling protein 2 (UCP2) …
[PDF][PDF] Antibodies as ion channel modulators and drugs
M Rogers - nanion.de
With current discussions about the changing dominance of small molecules vs biologics as
clinical therapeutics, it seems a good time to provide an overview of the history and current …
clinical therapeutics, it seems a good time to provide an overview of the history and current …