[HTML][HTML] Immunogenic cell death inducer peptides: A new approach for cancer therapy, current status and future perspectives
Abstract Immunogenic Cell Death (ICD) is a type of cell death that kills tumor cells by
stimulating the adaptive immune response against other tumor cells. ICD depends on the …
stimulating the adaptive immune response against other tumor cells. ICD depends on the …
Apoptosis Inhibitor 5: A Multifaceted Regulator of Cell Fate
H Abbas, DK Derkaoui, L Jeammet, E Adicéam… - Biomolecules, 2024 - mdpi.com
Apoptosis, or programmed cell death, is a fundamental process that maintains tissue
homeostasis, eliminates damaged or infected cells, and plays a crucial role in various …
homeostasis, eliminates damaged or infected cells, and plays a crucial role in various …
The γδ IEL effector API5 masks genetic susceptibility to Paneth cell death
Loss of Paneth cells and their antimicrobial granules compromises the intestinal epithelial
barrier and is associated with Crohn's disease, a major type of inflammatory bowel …
barrier and is associated with Crohn's disease, a major type of inflammatory bowel …
A cell-penetrating peptide targeting AAC-11 specifically induces cancer cells death
L Jagot-Lacoussiere, E Kotula, BO Villoutreix… - Cancer research, 2016 - AACR
AAC-11 is an antiapoptotic protein that is upregulated in most cancer cells. Increased
expression of AAC-11 confers a survival advantage when cancer cells are challenged with …
expression of AAC-11 confers a survival advantage when cancer cells are challenged with …
Regulation of mRNA export through API5 and nuclear FGF2 interaction
SM Bong, SH Bae, B Song, HR Gwak… - Nucleic acids …, 2020 - academic.oup.com
Abstract API5 (AP optosis I nhibitor 5) and nuclear FGF2 (F ibroblast G rowth F actor 2) are
upregulated in various human cancers and are correlated with poor prognosis. Although …
upregulated in various human cancers and are correlated with poor prognosis. Although …
Validation of AAC-11-derived peptide anti-tumor activity in a single graft sezary patient-derived xenograft mouse model
Sézary syndrome (SS) is an aggressive cutaneous T cell lymphoma with poor prognosis
mainly characterized by the expansion of a tumor CD4+ T cell clone in both skin and blood …
mainly characterized by the expansion of a tumor CD4+ T cell clone in both skin and blood …
Killing of Plasmodium Sporozoites by Basic Amphipathic α-Helical Fusion Peptides
MC Aguirre-Botero, E Aliprandini, A Gladston, O Pacios… - Microorganisms, 2024 - mdpi.com
Membranolytic molecules constitute the first line of innate immune defense against
pathogenic microorganisms. Plasmodium sporozoites are potentially exposed to these …
pathogenic microorganisms. Plasmodium sporozoites are potentially exposed to these …
Nucleoprotein of influenza A virus negatively impacts antiapoptotic protein API5 to enhance E2F1-dependent apoptosis and virus replication
Apoptosis of host cells profoundly influences virus propagation and dissemination, events
that are integral to influenza A virus (IAV) pathogenesis. The trigger for activation of …
that are integral to influenza A virus (IAV) pathogenesis. The trigger for activation of …
Apoptosis inhibitor 5 is an endogenous inhibitor of caspase‐2
Caspases are key enzymes responsible for mediating apoptotic cell death. Across species,
caspase‐2 is the most conserved caspase and stands out due to unique features. Apart from …
caspase‐2 is the most conserved caspase and stands out due to unique features. Apart from …
Protective Effects of Polydatin from Grapes and Reynoutria japonica Houtt. on Damaged Macrophages Treated with Acetaminophen
C Liu, W Wang, K Zhang, Q Liu, T Ma, L Tan, L Ma - Nutrients, 2022 - mdpi.com
The unregulated use of acetaminophen (APAP), an antipyretic and analgesic drug, harms
hepatocytes and kidney cells, leading to liver failure and acute kidney injury. Herein, we …
hepatocytes and kidney cells, leading to liver failure and acute kidney injury. Herein, we …