Childhood obesity has emerged as an important public health problem in the United States
and other countries in the world. Currently 1 in 3 children in the United States is afflicted with …

Prevalence of metabolic syndrome in children and adolescents is increasing, in parallel with
the increasing trends in obesity rates. Varying definitions of this syndrome have hindered the …

Abstract Cosponsoring Associations: The European Society of Endocrinology and the
Pediatric Endocrine Society. This guideline was funded by the Endocrine Society. Objective …

Severe obesity afflicts between 4% and 6% of all youth in the United States, and the
prevalence is increasing. Despite the serious immediate and long-term cardiovascular …

Background Gut microbiota modifiers may have beneficial effects of non‐alcoholic fatty liver
disease (NAFLD) but randomised controlled trials (RCT) are lacking in children. Aim To …

Abstract Glucagon-like peptide 1 (GLP-1) is a cleavage product of the pre-proglucagon gene
which is expressed in the α-cells of the pancreas, the L-cells of the intestine, and neurons …

The increased prevalence of adolescent obesity and associated short-term and long-term
complications emphasize the need for effective treatment. In this Review, we aim to describe …

Objectives To determine the weight, body mass index (BMI), cardiometabolic, and
gastrointestinal effects of glucagon-like peptide-1 (GLP-1) receptor agonists in children with …

A growing number of youth suffer from obesity and in particular severe obesity for which
intensive lifestyle intervention does not adequately reduce excess adiposity. A treatment gap …

Pediatric obesity is a highly prevalent chronic disease, which has traditionally been treated
with lifestyle therapy alone. Yet for many youth, lifestyle intervention as a monotherapy is …