Circuits for action and cognition: a view from the superior colliculus

MA Basso, PJ May - Annual review of vision science, 2017 - annualreviews.org
The superior colliculus is one of the most well-studied structures in the brain, and with each
new report, its proposed role in behavior seems to increase in complexity. Forty years of …

Cortical-subcortical interactions in goal-directed behavior

KG Cruz, YN Leow, NM Le, E Adam… - Physiological …, 2023 - journals.physiology.org
Flexibly selecting appropriate actions in response to complex, ever-changing environments
requires both cortical and subcortical regions, which are typically described as participating …

Basal ganglia–spinal cord pathway that commands locomotor gait asymmetries in mice

JM Cregg, SK Sidhu, R Leiras, O Kiehn - Nature Neuroscience, 2024 - nature.com
The basal ganglia are essential for executing motor actions. How the basal ganglia engage
spinal motor networks has remained elusive. Medullary Chx10 gigantocellular (Gi) neurons …

Causal role for the primate superior colliculus in the computation of evidence for perceptual decisions

EJ Jun, AR Bautista, MD Nunez, DC Allen, JH Tak… - Nature …, 2021 - nature.com
Trained monkeys performed a two-choice perceptual decision-making task in which they
reported the perceived orientation of a dynamic Glass pattern, before and after unilateral …

Divergent midbrain circuits orchestrate escape and freezing responses to looming stimuli in mice

C Shang, Z Chen, A Liu, Y Li, J Zhang, B Qu… - Nature …, 2018 - nature.com
Animals respond to environmental threats, eg looming visual stimuli, with innate defensive
behaviors such as escape and freezing. The key neural circuits that participate in the …

Transient stimulation of distinct subpopulations of striatal neurons mimics changes in action value

LH Tai, AM Lee, N Benavidez, A Bonci… - Nature neuroscience, 2012 - nature.com
In changing environments, animals must adaptively select actions to achieve their goals. In
tasks involving goal-directed action selection, striatal neural activity has been shown to …

Neural antecedents of self-initiated actions in secondary motor cortex

M Murakami, MI Vicente, GM Costa, ZF Mainen - Nature neuroscience, 2014 - nature.com
The neural origins of spontaneous or self-initiated actions are not well understood and their
interpretation is controversial. To address these issues, we used a task in which rats decide …

Corticostriatal neurons in auditory cortex drive decisions during auditory discrimination

P Znamenskiy, AM Zador - Nature, 2013 - nature.com
The neural pathways by which information about the acoustic world reaches the auditory
cortex are well characterized, but how auditory representations are transformed into motor …

Vision drives accurate approach behavior during prey capture in laboratory mice

JL Hoy, I Yavorska, M Wehr, CM Niell - Current Biology, 2016 - cell.com
The ability to genetically identify and manipulate neural circuits in the mouse is rapidly
advancing our understanding of visual processing in the mammalian brain [1, 2]. However …

Selective corticostriatal plasticity during acquisition of an auditory discrimination task

Q Xiong, P Znamenskiy, AM Zador - Nature, 2015 - nature.com
Perceptual decisions are based on the activity of sensory cortical neurons, but how
organisms learn to transform this activity into appropriate actions remains unknown …