The importance of ongoing international surveillance for Creutzfeldt–Jakob disease
N Watson, JP Brandel, A Green, P Hermann… - Nature Reviews …, 2021 - nature.com
Creutzfeldt–Jakob disease (CJD) is a rapidly progressive, fatal and transmissible
neurodegenerative disease associated with the accumulation of misfolded prion protein in …
neurodegenerative disease associated with the accumulation of misfolded prion protein in …
Implications of peptide assemblies in amyloid diseases
Neurodegenerative disorders and type 2 diabetes are global epidemics compromising the
quality of life of millions worldwide, with profound social and economic implications. Despite …
quality of life of millions worldwide, with profound social and economic implications. Despite …
First case of chronic wasting disease in Europe in a Norwegian free-ranging reindeer
Chronic wasting disease (CWD) is a fatal contagious prion disease in cervids that is
enzootic in some areas in North America. The disease has been found in deer, elk and …
enzootic in some areas in North America. The disease has been found in deer, elk and …
Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays
JM Wilham, CD Orrú, RA Bessen, R Atarashi… - PLoS …, 2010 - journals.plos.org
A major problem for the effective diagnosis and management of prion diseases is the lack of
rapid high-throughput assays to measure low levels of prions. Such measurements have …
rapid high-throughput assays to measure low levels of prions. Such measurements have …
Prions: protein aggregation and infectious diseases
A Aguzzi, AM Calella - Physiological reviews, 2009 - journals.physiology.org
Transmissible spongiform encephalopathies (TSEs) are inevitably lethal neurodegenerative
diseases that affect humans and a large variety of animals. The infectious agent responsible …
diseases that affect humans and a large variety of animals. The infectious agent responsible …
Risk assessment of the use of alternative animal and plant raw material resources in aquaculture feeds
BD Glencross, J Baily, MHG Berntssen… - Reviews in …, 2020 - Wiley Online Library
A wide range of raw materials are now used routinely in aquaculture feeds throughout the
world, primarily to supply protein and energy in the form of lipid from edible oils. Protein …
world, primarily to supply protein and energy in the form of lipid from edible oils. Protein …
Chronic wasting disease of cervids: current knowledge and future perspectives
NJ Haley, EA Hoover - Annu. Rev. Anim. Biosci., 2015 - annualreviews.org
A naturally occurring transmissible spongiform encephalopathy (TSE) of mule deer was first
reported in Colorado and Wyoming in 1967 and has since spread to other members of the …
reported in Colorado and Wyoming in 1967 and has since spread to other members of the …
Prion-like disorders: blurring the divide between transmissibility and infectivity
M Cushman, BS Johnson, OD King… - Journal of cell …, 2010 - journals.biologists.com
Prions are proteins that access self-templating amyloid forms, which confer phenotypic
changes that can spread from individual to individual within or between species. These …
changes that can spread from individual to individual within or between species. These …
Insights into prion strains and neurotoxicity
A Aguzzi, M Heikenwalder… - Nature reviews Molecular …, 2007 - nature.com
Transmissible spongiform encephalopathies (TSEs) are neurodegenerative diseases that
are caused by prions and affect humans and many animal species. It is now widely accepted …
are caused by prions and affect humans and many animal species. It is now widely accepted …
Molecular mechanisms of prion pathogenesis
A Aguzzi, C Sigurdson… - Annu. Rev. Pathol. Mech …, 2008 - annualreviews.org
Prion diseases are infectious neurodegenerative diseases occurring in humans and animals
with an invariably lethal outcome. One fundamental mechanistic event in prion diseases is …
with an invariably lethal outcome. One fundamental mechanistic event in prion diseases is …