Creutzfeldt–Jakob disease (CJD) is a rapidly progressive, fatal and transmissible
neurodegenerative disease associated with the accumulation of misfolded prion protein in …

Neurodegenerative disorders and type 2 diabetes are global epidemics compromising the
quality of life of millions worldwide, with profound social and economic implications. Despite …

Chronic wasting disease (CWD) is a fatal contagious prion disease in cervids that is
enzootic in some areas in North America. The disease has been found in deer, elk and …

A major problem for the effective diagnosis and management of prion diseases is the lack of
rapid high-throughput assays to measure low levels of prions. Such measurements have …

Transmissible spongiform encephalopathies (TSEs) are inevitably lethal neurodegenerative
diseases that affect humans and a large variety of animals. The infectious agent responsible …

A wide range of raw materials are now used routinely in aquaculture feeds throughout the
world, primarily to supply protein and energy in the form of lipid from edible oils. Protein …

A naturally occurring transmissible spongiform encephalopathy (TSE) of mule deer was first
reported in Colorado and Wyoming in 1967 and has since spread to other members of the …

Prions are proteins that access self-templating amyloid forms, which confer phenotypic
changes that can spread from individual to individual within or between species. These …

Transmissible spongiform encephalopathies (TSEs) are neurodegenerative diseases that
are caused by prions and affect humans and many animal species. It is now widely accepted …

Prion diseases are infectious neurodegenerative diseases occurring in humans and animals
with an invariably lethal outcome. One fundamental mechanistic event in prion diseases is …